Haldane’s Rule by Sexual Transformation in Caenorhabditis
Haldane's rule in C. briggsae x C. remanei broods was caused by sexual transformation; XX and XO hybrids were female. C. briggsae and C. remanei variants that partially suppress hybrid sexual transformation were identified. Effects of variant strains were cumulative. Hence, aberrant sex determination is a reproductive isolation mechanism in Caenorhabditis.
Baird, S. E.
(2002). Haldane’s Rule by Sexual Transformation in Caenorhabditis. Genetics, 161 (3), 1349-1353.