The clinical presentation of endocarditis is often nonspecific and variable, with potential to affect nearly every organ system in an indolent or fulminant course. The vast majority of endocarditis is infective; diagnosis relies on a set of explicit criteria, which include findings from blood culture, echocardiography, and close clinical observation. Unrecognized infective endocarditis has frequent complications and high mortality.
Rothman, R. E.,
Marco, C. A.,
& Yang, S.
(2016). Endocarditis. Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 8th Edition, 155.