Publication Date

2015

Document Type

Thesis

Committee Members

Kimberly Carhuatanta (Committee Member), Ryan Jankord (Committee Co-Chair), Larry Ream (Committee Member), Christopher Wyatt (Committee Co-Chair)

Degree Name

Master of Science (MS)

Abstract

Sleep deprivation causes many adverse effects on work performance. Many experiments in both human and rodent models reveal detriments that sleep deprivation has on learning and memory, including performance in a water radial arm maze (WRAM) task. This study utilizes the modified multiple platform method (MMPM) of sleep deprivation; rats were sleep deprived in order to study memory errors they may make during the WRAM task. The findings indicate that 6 hours of sleep deprivation for 2 five-day week periods did not affect performance in the WRAM task except on the initial day compared to the large platform group. The mRNA levels of BDNF and NGF were not changed. These findings are important since they help elucidate the relationship between sleep deprivation and environmental factors as well as supporting previous research conducted.

Page Count

43

Department or Program

Department of Neuroscience, Cell Biology, and Physiology


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