A Measure of Partial Association Between Disease and Genotype for the 2-Parent Problem

Authors

Harry J. Khamis, Wright State University - Main CampusFollow

Document Type

Article

Publication Date

1987

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Abstract

The two-parent disease-genotype association problem is studied from the point of view of a coefficient of association between the disease phenotype of the child and the disease phenotypes of the parents, in the presence of some genotypic information about the parents. This coefficient of partial association is derived, and certain tests of hypotheses are constructed. The results are shown to be useful in estimation of recurrence risks, and in understanding the nature of the association between child and parental disease phenotypes.

Repository Citation

Khamis, H. J. (1987). A Measure of Partial Association Between Disease and Genotype for the 2-Parent Problem. Communications in Statistics, Theory and Methods, 16 (7), 2029-2060.
https://corescholar.libraries.wright.edu/math/164

DOI

10.1080/03610928708829489