Repository Citation
Via, Garrhett G.; Brueggeman, David A.; Slack, Grant M.; Danias, James M.; and Jerele, Jennifer L., "Fluorescence-Guided Surgical Debridement of Chronic Osteomyelitis Utilizing Doxycycline Bone Labeling: A Technical Trick Revived" (2021). Medical Student Research Symposium Abstracts and Posters. 1.
https://corescholar.libraries.wright.edu/msrs/2021/poster_presentations_4/1
Start Date
29-4-2021 7:05 PM
End Date
29-4-2021 7:15 PM
Document Type
Poster
Description
The present manuscript discusses the concept of fluorescence-guided surgical debridement of chronic osteomyelitis in the orthopaedic patient based upon a two-fold mechanism, natural fluorescence of healthy bone combined with bone labeling by tetracyclines. The senior author prefers preoperative administration of oral doxycycline 100 mg twice daily for at least 1 month. The excitation source of choice is an ordinary blacklight, as this is both cost-effective and readily attainable. Intraoperatively, viable bone is noted to fluoresce a greenish hue which is then used to guide the debridement. Previous studies have demonstrated that bleeding bone is not a reliable indicator of a bone’s true metabolic state. This technical trick will offer orthopaedic surgeons an adjunct to their treatment algorithm of chronic osteomyelitis.
Abstract - Slack
Fluorescence-Guided Surgical Debridement of Chronic Osteomyelitis Utilizing Doxycycline Bone Labeling: A Technical Trick Revived
The present manuscript discusses the concept of fluorescence-guided surgical debridement of chronic osteomyelitis in the orthopaedic patient based upon a two-fold mechanism, natural fluorescence of healthy bone combined with bone labeling by tetracyclines. The senior author prefers preoperative administration of oral doxycycline 100 mg twice daily for at least 1 month. The excitation source of choice is an ordinary blacklight, as this is both cost-effective and readily attainable. Intraoperatively, viable bone is noted to fluoresce a greenish hue which is then used to guide the debridement. Previous studies have demonstrated that bleeding bone is not a reliable indicator of a bone’s true metabolic state. This technical trick will offer orthopaedic surgeons an adjunct to their treatment algorithm of chronic osteomyelitis.
