Title

Fluoride Ingestion During Pregnancy and Lactation: Morphological Effects on Maternal Rat Bone

Document Type

Article

Publication Date

1983

Abstract

Anorganic preparations of femurs from female rats, given 150 ppm fluoride [F-] in the drinking water for 10 wk prior to and during 1 subsequent pregnancy and lactation period, were examined by SEM [scanning electron microscopy] and compared to controls. The major difference seen was a marked increase in endosteal resorption. Presumably a decreased serum Ca concentration, caused by bone F- deposition along with a high demand on Ca under the influence of lactation, resulted in increased bone mineral mobilization from the endosteal surface.

Catalog Record

Share

COinS