Title

The Morphology and Distribution of Serotonin-Like Immunoreactive Fibers in the Cat Dorsal Column Nuclei

Document Type

Article

Publication Date

2-24-1987

Abstract

Fibers showing serotonin-like immunoreactivity (5-HT-LI) are demonstrated in the gracile, cuneate and external cuneate nuclei of the cat using avidin-biotinylated horseradish peroxidase and indirect fluorescence immunohistochemical methods. 5-HT-LI fibers are located in all cytoarchitectural subdivisions of the gracile and cuneate nuclei but are restricted to the medial half of the external cuneate nucleus. In all nuclei, 5-HT-LI fibers consist of long, varicose strands showing a wide range in the diameters of both varicosities and intervaricose segments. Results support the concept that serotonergic systems may be involved in the processing of non-noxious somatosensory submodalities.

DOI

10.1016/0304-3940(87)90137-6