Glial Modulation of CO₂ Chemosensory Excitability in the Retrotrapezoid Nucleus of Rodents

Authors

Joseph S. Erlichman
Robert W. Putnam, Wright State University - Main CampusFollow
James C. Leiter

Document Type

Book Chapter

Publication Date

2008

Abstract

We investigated the possibility that astrocytes modify the extracellular milieu and thereby modify the activity of central CO₂ chemosensory neurons. The ability of astrocytes to modify the extracellular milieu is heterogeneously distributed among chemosensory sites that have, at least nominally, the same function. The differences in astrocytic activity may make some central chemosensory sites better attuned to the local brain tissue environment and other chemosensory sites better suited to integrate chemosensory activity from multiple sites within and outside the central nervous system.

Repository Citation

Erlichman, J. S., Putnam, R. W., & Leiter, J. C. (2008). Glial Modulation of CO₂ Chemosensory Excitability in the Retrotrapezoid Nucleus of Rodents. Integration in Respiratory Control: From Genes to Systems, 605, 317-321.
https://corescholar.libraries.wright.edu/ncbp/714

DOI

10.1007/978-0-387-73693-8_55