Development and Evaluation of a Long-Term, Implantable, Electrically Actuated Left Ventricular Assist System: THI/Gould LVAS
Document Type
Article
Publication Date
2-1983
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Abstract
A long-term, implantable, electrically actuated left ventricular assist system (THI/Gould LVAS) is being developed and characterized in vitro and in vivo for utilization in patients with end-stage heart disease. This system consists of five major components: a long-term, implantable blood pump (THI E-type ALVAD); an electrical-mechanical energy converter (Gould Model V); a control unit with batteries; a volume compensation system; and an external power supply and monitoring unit. Two of these components (blood pump and electrical-mechanical energy converter) have been integrated, and are undergoing chronic in vivo evaluations in calves. Thus far, 44 pneumatically and electrically actuated THI/Gould LVAS evaluations have been performed. This experience has resulted in >6.5 years of actuation in vivo, with durations exceeding 1 year. System in vivo performance in terms of durability, mechanical reliability, hemodynamic effectiveness, and biocompatibility has been satisfactory. Demonstration of long-term (2-year) effectiveness in supporting the circulation is the ultimate goal.
Repository Citation
Norman, J. C.,
Igo, S. R.,
Turner, S. A.,
Scott, R. P.,
Urrutia, C. O.,
Frazier, O. H.,
Clay, W. C.,
& Chambers, J. A.
(1983). Development and Evaluation of a Long-Term, Implantable, Electrically Actuated Left Ventricular Assist System: THI/Gould LVAS. Artificial Organs, 7 (1), 64-73.
https://corescholar.libraries.wright.edu/surg/286
DOI
10.1111/j.1525-1594.1983.tb04160.x
