Cefonicid Concentrations in Serum and Atrial Tissue during Open-Heart Surgery
Document Type
Article
Publication Date
5-1983
Abstract
Cefonicid was administered intramuscularly 1 h before open-heart surgery to seven patients in doses of 1 g each and to six patients in doses of 2 g each. Cefonicid concentrations were measured in the right atrial biopsy and in serum at onset of surgery, at time of atrial biopsy, 15 min after starting cardiopulmonary bypass, and at completion of cardiopulmonary bypass. Concentrations in the atrial biopsy and in serum at all periods exceeded the minimal inhibitory concentrations for organisms most frequently responsible for postoperative infections.
Repository Citation
Scott, R. P.,
Connor, D. J.,
Norman, J. C.,
& Cooley, D. A.
(1983). Cefonicid Concentrations in Serum and Atrial Tissue during Open-Heart Surgery. Antimicrobial Agents and Chemotherapy, 23 (5), 790-792.
https://corescholar.libraries.wright.edu/surg/288
PMCID
PMC184821
