Title

Mechanisms of Natural Vitamin E, Alpha-Tocotrienol, in Pial Collateral Recruitment and Remodeling During Acute Ischemic Stroke

Document Type

Abstract

Publication Date

3-2011

Abstract

Vitamin E is a generic term for tocopherols and tocotrienols. The lesser characterized isoform á-tocotrienol (T3) exhibits neuroprotective properties not shared by tocopherols (TP). Previous work in a large animal model of stroke demonstrated that prophylactic supplementation of T3, but not TP, attenuates stroke mediated brain injury and improves pial collateral circulation.

Comments

Presented at the International Stroke Conference and Nursing Symposium, Los Angeles, CA, February 8-11, 2011.