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Submissions from 2020

Neuromuscular Junction Transmission Failure Is a Late Phenotype in Aging Mice, Deepti Chugh, Chitra C. Iyer, Xueyong Wang, Prameela Bobbili, Mark M. Rich, and W. David Arnold

Meta-analysis of biological variables’ impact on spinal motoneuron electrophysiology data, Morgan M. Highlander, John M. Allen, and Sherif M. Elbasiouny

Chronic Defects in Intraspinal Mechanisms of Spike Encoding by Spinal Motoneurons Following Chemotherapy, Stephen N. Housley, Paul Nardelli, Randal K. Powers, Mark M. Rich, and Timothy C. Cope

Central Role of Subthreshold Currents in Myotonia, Sabrina Metzger, Chris Dupont, Andrew A. Voss, and Mark M. Rich

Multi-Walled Carbon Nanotube Carpets as Scaffolds for u87mg Glioblastoma Multiforme Cell Growth, Soham D. Parikh, Soham Dave, Luping Huang, Wenhu Wang, Sharmila M. Mukhopadhyay, and Debra A. Mayes

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Effects of TRPM7 Kinase Inactivation in Macrophages, Jananie Rockwood, Pavani Beesetty, Masayuki Matsushita, and J. Ashot Kozak

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Depressed Neuromuscular Transmission Causes Weakness in Mice Lacking BK Potassium Channels, Xueyong Wang, Steven R.A. Burke, Robert J. Talmadge, Andrew A. Voss, and Mark M. Rich

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COVID 19 What You Need to Know, Dawn P. Wooley, Giancarlo Mariani, Craig Woolley, and Laura M. Luehrmann

Submissions from 2019

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Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation, Erica Tracey Akhter, Ronald W. Griffith, Arthur W. English, and Francisco J. Alvarez

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Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction, Renee E. Albers, Melissa R. Kaufman, Bryony V. Natale, Chanel Keoni, Kashmira Kulkarni-Datar, Sarah Min, Clintoria R. Williams, David R.C. Natale, and Thomas L. Brown

A Motor Physiology Recurrent Topic: Simplify Assumptions to Gain Extra Insight, Francisco J. Alvarez

Treatment of Myotonia Congenita With Retigabine in Mice, Chris Dupont, Kirsten S. Denman, Ahmed A. Hawash, Andrew A. Voss, and Mark M. Rich

Automated Cell-Type Classification and Death-Detection of Spinal Motoneurons, Mai Gamal, Mohamed H. Mousa, Seif Eldawlatly, and Sherif M. Elbasiouny

Genetic and Pharmacological Inactivation of Apical NA+-K+-2cl− Cotransporter 1 in Choroid Plexus Epithelial Cells Reveals the Physiological Function of the Cotransporter, Jeannine MC Gregoriades, Aaron Madaris, Francisco J. Alvarez, and Francisco J. Alvarez-Leefmans

Open-Label Trial of Ranolazine for the Treatment of Paramyotonia Congenita, Samantha Lorusso, David Kline, Amy Bartlett, Miriam Freimer, Julie Agriesti, Ahmed A. Hawash, Mark M. Rich, John T. Kissel, and W. David Arnold

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The Mechanistic Basis for Successful Spinal Cord Stimulation to Generate Steady Motor Outputs, Amr A. Mahrous, Mohamed H. Mousa, and Sherif M. Elbasiouny

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Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism, Travis M. Rotterman, Erica T. Akhter, Alicia R. Lane, Kathryn P. MacPherson, Violet V. Garcia, Malu G. Tansey, and Francisco J. Alvarez

Calcium Imaging of Parvalbumin Neurons in the Dorsal Root Ganglia, Marie C. Walters, Martha Sonner, Jessica H. Myers, and David R. Ladle

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Initial Characterization of the Indole-3-Carboxamide Bic-154 as a Fast Onset and Reversible ORAI Channel Blocker, Tetyana Zhelay, Kalina Szteyn, Elisa Liardo, Jae Eun Cheong, Steffi Koerner, Anil Ekkati, Lijun Sun, and J. Ashot Kozak

Submissions from 2018

Protect NIH's DNA Advisory Committee, Zach N. Adelman, Lorraine M. Albritton, Kathleen Boris-Lawrie, Michael J. Buchmeier, Paula Cannon, Mildred Cho, David DiGiusto, J Kevin Donahue, Howard J. Federoff, Marie-Louise Hammarskjold, Angelica D. Hardison, Benhur Lee, Dean Anthony Lee, Matthew H. Porteus, Lainie Friedman Ross, Susan R. Ross, Dawn P. Wooley, and Laurie Zoloth

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TGF-β induces Smad2 phosphorylation, ARE induction, and trophoblast differentiation, Renee E. Albers, Kaisa Selesniemi, David R.C. Natale, and Thomas L. Brown

Gestational differences in murine placenta: Glycolytic metabolism and pregnancy parameters, Renee E. Albers, Christopher A. Waker, Chanel Keoni, Melissa R. Kaufman, Michael A. Bottomley, Sarah Min, David R. Natale, and Thomas L. Brown

The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors, John M. Allen and Sherif M. Elbasiouny

Spinal Interneurons “à La Carte”, Francisco J. Alvarez

N-Acetylcysteine Modulation of Mitochondrial Respiration and Blood Brain Barrier Permeability Is Time Dependent and Cell Type Specific, Alim S El Amouri, Christopher A. Waker, Luping Huang, Cameron L. Smith, and Debra A. Mayes

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Inactivation of TRPM7 Kinase in Mice Results in Enlarged Spleens, Reduced T-Cell Proliferation and Diminished Store-Operated Calcium Entry, Pavani Beesetty, Krystyna Blanka Wieczerzak, Jennifer Gibson, Taku Kaitsuka, Charles Tuan Luu, Masayuki Matsushita, and J. Ashot Kozak

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The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis, S. Shekar Dukkipati, Teresa L. Garrett, and Sherif M. Elbasiouny

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Gender- and Region-Specific Changes in Estrogen Signaling in Aging Rat Brain Mitochondria, Christopher M. Evola, Tanner L. Hudson, Luping Huang, Adrian M. Corbett, and Debra A. Mayes

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Preventing Acute Asthmatic Symptoms by Targeting a Neuronal Mechanism Involving Carotid Body Lysophosphatidic Acid Receptors, Nicholas G. Jendzjowsky, Arijit Roy, Nicole O. Barioni, Margaret M. Kelly, Francis HY Green, Christopher N. Wyatt, Richard L. Pye, Luana Tenorio Lopes, and Richard A. Wilson

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Modulation of SK channels regulates locomotor alternating bursting activity in the functionally-mature spinal cord, Amr A. Mahrou and Sherif M. Elbasiouny

Activation of TRPV4 Stimulates Transepithelial Ion Flux in a Porcine Choroid Plexus Cell Line, Daniel Preston, Stefanie Simpson, Dan R. Halm, Alexandra Hochestetler, Christian Schwerk, Horst Schroten, and Bonnie L. Blazer-Yost

High Fat Feeding in Rats Alters Respiratory Parameters by a Mechanism That Is Unlikely to Be Mediated by Carotid Body Type I Cells, Ryan J. Rakoczy, Richard L. Pye, Tariq Hasan Fayyad, Joseph Michael Santin, Barbara L. Barr, and Christopher N. Wyatt

Facilitation of Antagonist Motor Output Through Short-Latency Sensory Pathways During Postnatal Development in the Mouse, Patrick M. Sonner and David R. Ladle

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Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction, Xueyong Wang, J. Michael McIntosh, and Mark M. Rich

Homeostatic Synaptic Plasticity at the Neuromuscular Junction in Myasthenia Gravis, Xueyong Wang and Mark M. Rich

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TRPM7 Current Inactivation: Evidence for Inside-Out Signaling, Tetyana Zhelay and J. Ashot Kozak

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Depletion of Plasma Membrane–Associated Phosphoinositides Mimics Inhibition of TRPM7 Channels by Cytosolic Mg2+, Spermine, and pH, Tetyana Zhelay, Krystyna Blanka Wieczerzak, Pavani Beesetty, Gerald M. Alter, Masayuki Matsushita, and J. Ashot Kozak

Submissions from 2017

Gephyrin and the Regulation of Synaptic Strength and Dynamics at Glycinergic Inhibitory Synapses, Francisco J. Alvarez

Open-Label Trial of Ranolazine for the Treatment of Myotonia Congenita, W. David Arnold, David Kline, Alan Sanderson, Ahmed A. Hawash, Amy Bartlett, Kevin R. Novak, Mark M. Rich, and John T. Kissel

Ventilatory and Chemoreceptor Responses to Hypercapnia in Neonatal Rats Chronically Exposed to Moderate Hyperoxia, Ryan W. Bavis, Ke-yong Li, Kathryn J. DeAngelis, Ryan J. March, Josefine A. Wallace, Sarah Logan, and Robert W. Putnam

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Regulation of TRPM7 by Cytosolic Mg2+ and pH: Insights from VSP Expression, Pavani Beesetty, Krystyna Blanka Wieczerzak, Tatyana Zhelay, Taku Kaitsuka, Masayuki Matsushita, and J. Ashot Kozak

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Experimental design and data analysis issues contribute to inconsistent results of C-bouton changes in amyotrophic lateral sclerosis, S. Shekar Dukkipati, Aouatef Chihi, Yiwen Wang, and Sherif M. Elbasiouny

Cross-Disciplinary Medical Advances with Neuroengineering: Challenges Spur Development of Unique Rehabilitative and Therapeutic Interventions, Sherif Elbasiouny

Characterization of Calbindin D28k Expressing Interneurons in the Ventral Horn of the Mouse Spinal Cord, Taylor L. Floyd, Yiyun Dai, and David R. Ladle

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Survival and Growth of C57BL/6J Mice Lacking the BK Channel, Kcnma1: Lower Adult Body Weight Occurs Together with Higher Body Fat, Susan T. Halm, Michael A. Bottomley, Mohammed M. Almutairi, Mauricio Di Fulvio, and Dan R. Halm

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Inhibiting Persistent Inward Sodium Currents Prevents Myotonia, Ahmed A. Hawash, Andrew A. Voss, and Mark M. Rich

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Depressed Synaptic Transmission and Reduced Vesicle Release Sites in Huntington's Disease Neuromuscular Junctions, Ahmad Khedraki, Eric J. Reed, Shannon H. Romer, Qingbo Wang, William Romine, Mark M. Rich, Robert J. Talmadge, and Andrew A. Voss

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The Neuronal K+CL− Co-Transporter 2 (Slc12a5) Modulates Insulin Secretion, Shams Kursan, Timothy S. McMillen, Pavani Beesetty, Eduardo Dias-Junior, Mohammed M. Almutairi, Abu A. Sajib, J. Ashot Kozak, Lydia Aguilar-Bryan, and Mauicio Di Fulvio

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SK channel inhibition mediates the initiation and amplitude modulation of synchronized burst firing in the spinal cord, Amr A. Mahrous and Sherif M. Elbasiouny

Simulation of dendritic L-type ca channels' warm-up phenomenon in spinal motoneurons, Mohamed H. Mousa, Ahmed H. Kandil, and Sherif M. Elbasiouny

Increasing Motor Neuron Excitability to Treat Weakness in Sepsis, Paul Nardelli, Randall Powers, Tim C. Cope, and Mark M. Rich

Dicer Maintains the Identity and Function of Proprioceptive Sensory Neurons, Sean M. O'Toole, Monica M. Ferrer, Jennifer Mekonnen, Haihan Zhang, Yasuyuki Shima, David R. Ladle, and Sacha B. Nelson

Refining Forelimb Asymmetry Analysis: Correlation with Montoya Staircase Contralateral Function Post-stroke, Moner A. Ragas, Devipriyanka Nagarajan, and Adrian M. Corbett

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Distinct Roles for Motor Neuron Autophagy Early and Late in the sod1g93a Mouse Model of Als, Noam D. Rudnick, Christopher J. Griffey, Paolo Guarnieri, Valeria Gerbino, Xueyong Wang, Jason A. Piersaint, Juan Carlos Tapia, Mark M. Rich, and Tom Maniatis

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VGLUT1 Synapses and P-Boutons on Regenerating Motoneurons After Nerve Crush, Adam J. Schultz, Travis M. Rotterman, Anirudh Dwarakanath, and Francisco J. Alvarez

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Analysis of Proprioceptive Sensory Innervation of the Mouse Soleus: A Whole-Mount Muscle Approach, Martha Jean Sonner, Marie C. Walters, and David R. Ladle

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Mixed-mode Oscillations in Pyramidal Neurons Under Antiepileptic Drug Conditions, Babak V-Ghaffari, M. Kouhnavard, and Sherif M. Elbasiouny

AMPK Knockdown in Placental Labyrinthine Progenitor Cells Results in Restriction of Critical Energy Resources and Terminal Differentiation Failure, Christopher A. Waker, Renee E. Albers, Richard L. Pye, Savannah R. Doliboa, Christopher N. Wyatt, Thomas L. Brown, and Debra A. Mayes

AMPK Knockdown in Placental Labyrinthine Progenitor Cells Results in Restriction of Critical Energy Resources and Terminal Differentiation Failure, Christopher A. Waker, Renee E. Albers, Richard L. Pye, Savannah R. Doliboa, Christopher N. Wyatt, Thomas L. Brown, and Debra A. Mayes

A Directed Evolution Approach to Select for Novel Adeno-Associated Virus Capsids on an HIV-1 Producer T Cell Line, Dawn P. Wooley, Priyanka Sharma, John R. Weinstein, Poornima Kotha Lakshmi Narayan, David V. Schaffer, and Katherine J.D.A. Excoffon

Duplex Quantitative Polymerase Chain Reaction Assay for Detection of Adenoviral and Lentiviral Vectors, Dawn P. Wooley and Swathee Vasanth

Submissions from 2016

Mitogenic Activation and Proliferation of T Lymphocytes in TRPM7 Kinase-Dead Mutant Mice, Pavani Beesetty, Masayuki Matsushita, and J. Ashot Kozak

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Mitogenic Activation and Proliferation of T Lymphocytes in TRPM7 Kinase-Dead Mutant Mice, Pavani Beesetty, Masayuki Matsushita, and J. Ashot Kozak

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Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs, Jennifer Gibson, Pavani Beesetty, Sulentic Courtney, and J. Ashot Kozak

Physiologic Influences of Transepithelial K+ Secretion, Dan R. Halm

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Synapse Formation in Monosynaptic Sensory–Motor Connections Is Regulated by Presynaptic Rho GTPase Cdc42, Fumiyasu Imai, David R. Ladle, Jennifer R. Leslie, Xin Duan, Tilat A. Rizvi, Georgianne M. Ciraolo, Yi Zheng, and Yutaka Yoshida

Anatomical and Functional Connections between the Locus Coeruleus and the Nucleus Tractus Solitarius in Neonatal Rats, Luana Tenorio Lopes, Luis Gustavo Alexandre Patrone, K. -Y. Li, Ann N. Imber, Cathy D. Graham, Luciane H. Gargaglioni, and Robert W. Putnam

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Reduced Motor Neuron Excitability is an Important Contributor to Weakness in a Rat Model of Sepsis, Paul Nardelli, Jacob A. Vincent, Randall K. Powers, Timothy C. Cope, and Mark M. Rich

Appropriate Timing of Fluoxetine and Statin Administration Reduces the Risk of Secondary Hemorrhagic Infarct After Ischemic Stroke, Moner A. Ragas, Maria Helen Harley Balch, Danny Wright, Amber Lee Hensley, Kenny Reynolds, Bryce Kerr, and Adrian M. Corbett

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Risks Associated With Lentiviral Vector Exposures and Prevention Strategies, Ryan Schlimgen, John Howard, Dawn P. Wooley, Maureen Thompson, Lindsey Baden, Otto Yang, David Christiani, Gustavo Mostoslavsky, David Diamond, Elizabeth Gilman, Karen Byers, Thomas Winters, Jeffrey A. Gelfand, Gary Fujimoto, T Warner Hudson, and Jatin M. Vyas

Id2 Mediates Differentiation of Labyrinthine Placental Progenitor Cell Line, SM10, Kaisa Selesniemi, Renee E. Albers, and Thomas L. Brown

Role of Primary Afferents in the Developmental Regulation of Motor Axon Synapse Numbers on Renshaw Cells, Valerie C. Siembab, Laura Gomez-Perez, Travis M. Rotterman, Neil A. Shneider, and Francisco J. Alvarez

Adrenaline Release Evokes Hyperpnoea and an Increase in Ventilatory CO2 Sensitivity during Hypoglycaemia: A Role for the Carotid Body, Emma L. Thompson, Clare J. Ray, Andrew P. Holmes, Richard L. Pye, Christopher N. Wyatt, Andrew M. Coney, and Prem Kumar

Microglial Acid Sensing Regulates Carbon Dioxide-Evoked Fear, Lauren Larke Vollmer, Sriparna Ghosal, Jennifer L. McGuire, Rebecca L. Ahlbrand, Ke-yong Li, Joseph Michael Santin, Christine A. Ratliff-Rang, Luis Gustavo Alexandre Patrone, Jennifer Rush, Ian P. Lewkowich, James P. Herman, Robert W. Putnam, and Renu Sah

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Reversible Recruitment of a Homeostatic Reserve Pool of Synaptic Vesicles Underlies Rapid Homeostatic Plasticity of Quantal Content, Xueyong Wang, Martin J. Pinter, and Mark M. Rich

Submissions from 2015

Placental-Specific Hypoxia Inducible Factor-1 alpha as a Model of Preeclampsia, Renee E. Albers, Melissa R. Kaufman, Chanel Keoni, Martha Hughes, Bryony Natale, David Natale, and Thomas L. Brown

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Appropriate Timing of Fluoxetine and Statin Delivery Reduces the Risk of Secondary Bleeding in Ischemic Stroke Rats, Maria Helen Harley Balch, Moner A. Ragas, Danny Wright, Kenny Reynolds, Bryce Kerr, and Adrian M. Corbett

Distinct Muscle Apoptotic Pathways are Activated in Muscles with Different Fiber Types in a Rat Model of Critical Illness Myopathy, Benjamin T. Barnes, Amy L. Confides, Mark M. Rich, and Esther E. Dupont-Versteegden

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M1 and M2 Myeloid Cells in Inflammation, Nancy J. Bigley

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Putative Roles of SOCS1: SOCS 3 Ratios in Development and Resolution of a Herpesvirus Lesion, Nancy J. Bigley

Morphologically Detailed Motoneuron Models, Sherif M. Elbasiouny

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Personality Profiles of Rural Longitudinal Integrated Clerkship Students Who Choose Family Medicine, Diann S. Eley, Kathleen Dwyer Brooks, Therese M. Zink, and C. Robert Cloninger

Aldosterone and Beta-Adrenergic Activation of Colonic K+ Secretion Requires BK Channels (K(Ca)1.1), Susan T. Halm and Dan R. Halm

The Transformation of Synaptic to System Plasticity in Motor Output from the Sacral Cord of the Adult Mouse, Mingchen C. Jiang, Sherif M. Elbasiouny, William F. Collins III, and C. J. Heckman

The CamKKβ Inhibitor STO609 Causes Artefacts in Calcium Imaging and Selectively Inhibits BKCa in Mouse Carotid Body Type I Cells, Jennifer G. Jurcsisn, Richard L. Pye, Jon Ali, Barbara L. Barr, and Christopher N. Wyatt

Effects of Inactivation of TRPM7 Kinase Activity on its Channel Activity in Mice, Taku Kaitsuka, Chiaki Katagiri, Pavani Beesetty, Kenji Nakamura, Siham Hourani, Kazuhito Tomizawa, J. Ashot Kozak, and Masayuki Matsushita

Responses of Cortical Extrastriate Area 21a Neurons Specialized in Motion Detection, D. K. Khachvankian, H. R. Aslanian, Bella A. Harutiunian-Kozak, A. L. Ghazaryan, and J. Ashot Kozak

ED Patient Satisfaction: Factors Associated with Satisfaction with Care, Catherine A. Marco, Andy Davis, Sylvia L. Chang, Dennis Mann, and James E. Olson

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Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse, Vicki L. McGovern, Aurelie Massoni-Laporte, Xueyong Wang, Thanh T. Le, Hao T. Le, Mark M. Rich, and Arthur H. M. Burghes

Acutely Administered Leptin Increases [Ca2+]i and BKCa Currents But Does Not Alter Chemosensory Behavior in Rat Carotid Body Type I Cells, Richard L. Pye, Eric J. Dunn, Ellen M. Ricker, Jennifer G. Jurcsisn, Barbara L. Barr, and Christopher N. Wyatt

Intranasal Naloxone Administration by Police First Responders is Associated with Decreased Opioid Overdose Deaths, Jessica Rando, Derek Broering, James E. Olson, Catherine Marco, and Stephen B. Evans

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SOCS1/3 Expression Levels in HSV-1-Infected, Cytokine-Polarized and -Unpolarized Macrophages, Adam Craig Reichard, Nagarjuna Reddy Cheemarla, and Nancy J. Bigley

Selective mu and kappa Opioid Agonists Inhibit Voltage-Gated Ca2+ Entry in Isolated Neonatal Rat Carotid Body Type I Cells, Ellen M. Ricker, Richard L. Pye, Barbara L. Barr, and Christopher N. Wyatt

Complex Impairment of IA Muscle Proprioceptors following Traumatic or Neurotoxic Injury, Jacob A. Vincent, Paul Nardelli, Hanna M. Gabriel, Adam S. Deardorff, and Timothy C. Cope

Submissions from 2014

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Complexity of Interferon-γ Interactions with HSV-1, Nancy J. Bigley

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Swimming Against the Tide: Investigations of the C-Bouton Synapse, Adam S. Deardorff, Shannon H. Romer, Patrick M. Sonner, and Robert E. W. Fyffe

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Adult Spinal Motoneurones are not Hyperexcitable in a Mouse Model of Inherited Amyotrophic Lateral Sclerosis, Nicolas Delestrée, Marin Manuel, Caroline Iglesias, Sherif M. Elbasiouny, C. J. Heckman, and Daniel Zytnicki

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Development of Modified Cable Models to Simulate Accurate Neuronal Active Behaviors, Sherif M. Elbasiouny

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A HCO3-Dependent Mechanism Involving Soluble Adenylyl Cyclase for the Activation of Ca2+ Currents in Locus Coeruleus Neurons, Ann Nicole Imber, Joseph Michael Santin, Cathy D. Graham, and Robert W. Putnam

Decreased Cardiac Excitability Secondary to Reduction of Sodium Current May Be a Significant Contributor to Reduced Contractility in a Rat Model of Sepsis, Andrew G. Koesters, Kathrin L. Engisch, and Mark M. Rich