Document Type

Poster

Publication Date

10-1-2023

Identifier/URL

39891640 (Pure)

Abstract

Pretibial myxedema presents with indurated nodules or plaques that can be erythematous or vary in color from purple-brown to yellow. It is noted that a peau d’orange appearanceis a characteristic finding. These lesions are typically located on the anterolateral aspect of the lower legs. Non-pitting edema of the shins that evolves into elephantiasis is anotherpotential presentation seen in pretibial myxedema. It is often associated with hyperthyroidism, particularly Graves disease and is more commonly seen in women than men.Typically, it presents during the third or fourth decade of life. Differential diagnoses include but are not limited to stasis dermatitis, hypertrophic lichen planus, cutaneous mucinosis,lymphedema, and lipedema. The association with Graves/hyperthyroidism and the presentation can usually be helpful in distinguishing pretibial myxedema from the others;however, occasionally, the presentation may be atypical.


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