Document Type
Poster
Publication Date
4-28-2022
Identifier/URL
39891375 (Pure)
Abstract
Disseminated intravascular coagulopathy (DIC) is the widespread deposition of thrombin and fibrin in microvascular circulation. It is a condition in which clots form throughout the body leading to blockage of small blood vessels. The pathologic clotting in DIC is due to the consumption of coagulation factors and platelets. Patients can present with complications of bleeding or vascular thrombi. Most common causes of DIC include sepsis, malignancy, pregnancy complications, major trauma, and surgery.
Repository Citation
Gnyawali, B.,
Borchers, C. E.,
Doell, S.,
& House, K.
(2022). A Case of Blue Toes: DIC as the Initial Presentation of Metastatic Pancreatic Adenocarcinoma. , Lab findings will show an elevated d-dimer/PT/aPTT/INR, low fibrinogen/platelets, and microangiopathic hemolytic anemia. The management consists of identifying and treating the underlying disease. Blood products are given to patients with bleeding diathesis. Cryoprecipitate is given for fibrinogen <100mg/dll, FFP for prolonged PT/aPTT, Platelets, recombinant activate protein C, Protein C concentrate depending on the lab results. Signs of thrombosis without hemorrhage is an indication for anticoagulation..
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