The control of Aedes aegypti (A. aegypti), the primary vector for dengue virus, requires effective larvicidal agents to target larvae breeding in various water sources. This study aimed to assess the effectiveness of Copper Oxide Nanoparticles (CuO-NPs) as larvicidal agents against A. aegypti larvae in a laboratory setup. Larvae were exposed to CuO-NPs at five contrasting concentrations (0, 5, 10, 20, and 30 mg/l). Twenty-five fourth instar larvae were subjected to each concentration with three replicates and one control with the same number (n=25) of larvae under optimum laboratory conditions. The larval mortality was calculated after 24 hours. Mortality rates increased concentration-dependently, with an average of 75 % mortality rates at 30 % concentration showing the highest rate, and LC50 and LC90 were 7.9 mg/l and 27.8 mg/l, respectively. The findings of this study endorse the application of CuO-NP to control mosquito larvae as an environmentally friendly and cost-effective method. Further studies are warranted to explore the long-term effects, environmental impact, and potential application of CuO-NPs in field settings.

Article History

Received: Jan 07, 2024; Accepted: Feb 13, 2024; Published: Mar 30, 2024.

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