Biological control has attained immense significance. Biological control is not unknown. It has a past history of successes. Natural control consists of two major components: environmental factors (abiotic) and natural enemies (biotic). Integrated Pest Management or Crop Management is considered a valuable tool in food security. It has not only been used in Pakistan but also Pakistani biotic agents have been used elsewhere in the world giving substantial economic control. These have been mainly used in the USA. With World Trade Organization protocols in operation, biological control will be of much significance. Import and export of natural enemies will be up scaling in recent times.