Divulging the Antimicrobial and Antidiabetic Potential of Bombax ceiba L.

Authors

Hafiz Tahsin Ullah Jan, Department of Pharmacy, Quaid-i-azam University, Islamabad, PakistanFollow
Syeda Saniya Zahra, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University (45320), Islamabad, PakistanFollow
Bakht Nasir, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University (45320), Islamabad, PakistanFollow
Muhammad Waleed Baig, Department of Pharmacy, Quaid-i-Azam University ISlamabad, PakistanFollow
Madiha Ahmed, Shifa College of pharmaceutical sciences, Shifa tameer-e-millat university,Islamabad, PakistanFollow

Abstract

Current study is intended to investigate the antimicrobial and antidiabetic potential of Bombax ceiba L. Antileishmanial potential was assessed via MTT colorimetric method while antifungal activities were found out through disc diffusion method. The antidiabetic potential was investigated by α-amylase inhibition assay. Considerable antifungal activity (in the range of 10-12 mm ZOI) was demonstrated by CH: M extracts of both flower and stem bark, and CH extract of root bark against A. niger Whereas M: EA, AC extracts of leaf, EA extract of stem bark, NH, CH:E, M:EA extracts of root bark and NH extract of root wood exhibited the antifungal potential (ZOI from 10-12 mm) against F. solani. The most potent α-amylase inhibitory activity was shown by EA extract of leaf part with 66.69 ± 0.95% inhibition (IC₅₀ 190 ± 4.5 µg/ml). Selected plant is a potential source of antileishmanial, antifungal and antidiabetic agents. This information can be further utilized for the purpose of bioactivity guided isolation of biologically active principles of B. ceiba L.

DOI

10.35691/JBM.7102.0073

Recommended Citation

Jan, H., Zahra, S. S., Nasir, B., Baig, M., & Ahmed, M. (2017). Divulging the Antimicrobial and Antidiabetic Potential of Bombax ceiba L., Journal of Bioresource Management, 4 (3).
DOI: 10.35691/JBM.7102.0073