Current study was intended to investigate the cytotoxic potential of Bombax ceiba L.by executing a wide range of in vitro assays. Brine shrimp lethality assay showed that stem wood’s chloroform (CH) extract was highly toxic (LC50 42.41 ± 3.40 µg/ml) followed by acetone : ethyl acetate (AC:EA) extract with LC50 value of 72.92 ± 4.41 µg/ml. n-Hexane (NH) extract of root wood part caused 70.95 ± 1.77% inhibition of THP-1 cell line at 20 μg/ml concentration (IC50 15 ± 0.56 µg/ml). NH and CH extracts of stem wood part showed promising results in protein kinase inhibitory assay with 21 ± 1.2 and 29 ± 1 mm bald ZOI (MIC= 50 µg/disc) respectively. The present findings revealed that CH and NH extracts of stem wood as well as root wood part as an enriched source of phytochemicals possessing cytotoxic potential.
Tahsin Ullah Jan, H.,
& Zahra, S.
Revealing the Cytotoxic Potential of Medicinal Folklore: Bombax Ceiba L.,
Journal of Bioresource Management, 4