With the aim to assess the floristic population diversity, distribution and therapeutic properties in the Ziban region (Algeria), a survey was conducted along two successive study years in the main area. The objective of this study was to contribute to the knowledge and description of this plant groups with exhaustive inventory spontaneous vegetation. In order to study the dynamics of medicinal plants, we used a quantitative method based essentially on the classic technique of linear surveys and floristic inventory using the minimum area method. The results showed that the floristic procession of medicinal plants is represented by 21 species belonging to the 13 families, with a total of 31 species for the 08 study stations, which represents 68% of the total procession. The results obtained showed that the overall recovery is higher at the Ain Ben Noui station with 69%, even if the clumps of Aristida pungens, Atractylis serratuloides and Atriplexhalimus are isolated and scattered. The lowest overall coverage at the Oumache station is less than 21%, as it is an area with sandy soils. The species that contribute most to the recovery of mobile sand accumulations is Astragalus armatus with a rate of 76.19% at the Ain Ben Noui station. Frequency results allowed us to say that Atriplex halimus and Zizyphus lotus are the ubiquitous species (100% of the surveys). On the other hand, Nitraria retusa, Teucrium polium, Shismus barbatus, Sueda mollis and Halocnemum strobilaceum are the species present in only one survey.