Undesired Effects of Bioinsecticides Molecules in Wistar Rats: Case of Spirotetramat, Citrulus Colocynthis and Cleome Arabica Extracts

Authors

Boublata Nour El Iméne, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Manel Bekhakheche, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Habbachi Sarra, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Saadane Fatma Zohra, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Bouzar Abir, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Habbachi Wafa, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, AlgeriaFollow
Rebbas Khellaf, Department of Biology, Faculty of Sciences, University Med Boudiaf, M’Sila 28000, Algeria.Follow
Tahraoui Abedkrim, Department of Biology, Faculty of Sciences, University Badji Mokhtar, Annaba 23000, Algeria.Follow

Abstract

The use of pesticides is becoming an indispensable technique in most agricultural practices, regardless of the level of development of the country. Currently, the pesticides used are often less toxic and more specific and are based on insect physiology. Recent studies indicate that pesticide intoxication induces oxidative stress. This work aims to study the neurobehavioral consequences of the administration of two insecticides currently widely used in agriculture: spirotetramat (an inhibitor of lipid synthesis in insects) and the ethanolic extract of Citrullus colocynthis (a plant endemic to the Algerian Sahara) and the ethanolic extract of Cleome arabica (Capparidaceae) The different behavioral tests (elevated cross maze, open fields and forced swimming) show that the have a significant impact on the degree of anxiety of rodents.These products significantly influence the biochemical parameters (blood sugar, cholesterol, triglycerides, urea, creatinine), the hormone Adreno CorticoTropic Hormone, acetylcholine esterase, immune parameters and organ weight.

DOI

https://doi.org/10.35691/JBM.1202.0201

Article History

Received: May 21, 2021; Accepted: July 1, 2021; Published: Oct 13, 2021

Recommended Citation

Nour El Iméne, B., Bekhakheche, M., Sarra, H., Fatma Zohra, S., Abir, B., Wafa, H., Khellaf, R., & Abedkrim, T. (2021). Undesired Effects of Bioinsecticides Molecules in Wistar Rats: Case of Spirotetramat, Citrulus Colocynthis and Cleome Arabica Extracts, Journal of Bioresource Management, 8 (4).
DOI: https://doi.org/10.35691/JBM.1202.0201