A Review on Empirical Approach to Therapeutic Recombinant Protein Production Factories: Applications, Pharmacokinetics and Challenges

Authors

Zahra Naz, School of Biological Sciences, University of the Punjab, Lahore, Pakistan.Follow
Ambreen Kanwal, School of Biological Sciences, University of the Punjab, Lahore, Pakistan.Follow
Asima Tayyeb, School of Biological Sciences, University of the Punjab, Lahore, Pakistan.Follow

Abstract

Major portion of the proteins in a cell refers to their critical roles in metabolism of the living body. Proteins dysfunction results in the severe disorders which need to be treated in time. For this, respective proteins can be extracted by the external sources and be supplied to the human beings. Such medicinal proteins are known as therapeutic proteins (TPs). This review summarizes some of the key areas about these miracle proteins like their types, classification, production factories, routes of administration, pharmacokinetics, and potential applications. Furthermore, challenges and hurdles faced in getting a potential protein drug, its FDA approval and commercial availability are also highlighted for further research.

Article History

Received: Aug 16, 2021; Accepted: Sep 28, 2022; Published: March 24, 2022

Recommended Citation

Naz, Z., Kanwal, A., & Tayyeb, A. (2022). A Review on Empirical Approach to Therapeutic Recombinant Protein Production Factories: Applications, Pharmacokinetics and Challenges, Journal of Bioresource Management, 9 (1).