Article Title
Prevalence and Antibiotic Sensitivity Pattern of Bacterial Isolates from Catheterized Uti Patients: A Local Study
Abstract
Prevalence and multidrug resistance among bacteria in catheter-associated urinary tract infections has been on the rise in recent times. Hence, the prevalence rate and antibacterial susceptibility of bacteria in catheter-associated urinary tract infections in ICU patients was evaluated. A total of 120 patients admitted to the ICU of Nishtar Hospital, Multan were recruited for this study. Both gram positive and gram negative bacterial isolates were characterized based on biochemical tests including catalase test, oxidase test, indole test, TSI test, citrate test, coagulase test and growth on 6.5% NaCl agar. The prevalence of bacterial species was Escherichia coli (32%), Staphylococcus aureus (26%), Pseudomonas spp. (18%), Proteus spp. (14%) and Enterococcus spp. (2%). A considerable resistance pattern against commonly prescribed antibiotics was observed. Gram negative bacteria showed resistance to ciprofloxacin, piperacillin-tazobactam and amikacin and susceptibility to imipenem, tigecycline and polymixin. Gram positive bacteria showed resistance to antibiotics such as piperacillin-tazobactam, ampicillin, gentamicin, oxacillin and ceftazidime suggesting the ineffectiveness of these antibiotics for treating bacterial infections among CAUTI patients and demonstrating the latest trends in antimicrobial drug resistance profile in local population.
