Prevalence and Evaluation of Multidrug Resistance Pattern of Pseudomonas Aeruginosa among Critical and Non-Critical Areas at a Tertiary Care hospital of Multan

Authors

Romah Ishfaq, Department of Pathology, Nishtar Medical University, Multan, PakistanFollow
Hubza Ruatt Khan, Department of Microbiology and Molecular Genetics, The Women University, Multan, PakistanFollow
Mehvish Javeed, Department of Microbiology and Molecular Genetics, The Women University, Multan, PakistanFollow
Muhammad Ikrama Tanveer, Nawaz Sharif Medical College, Gujrat, PakistanFollow
Asma Ashraf, Department of Microbiology and Molecular Genetics, The Women University, Multan, PakistanFollow

Abstract

Pseudomonas aeruginosa is an extremely wide spread microorganism linked to nosocomial illnesses. Effective inspection of variations in antimicrobial resistance patterns of P. aeruginosa is vital for selecting suitable antimicrobial drugs for pragmatic treatment. The current research has been performed for assessing antimicrobial sensitivity profile of P. aeruginosa isolated as of a variety of medical specimens collected from critical and non-critical admitted patients of Nishtar Hospital, Multan. The isolates were detected utilizing standard lab practices, as well as the sensitivity was examined employing Kirby-Bauer disk diffusion method corresponding to Clinical and Laboratory Standard Institute (CLSI) recommendations 2019. Out of 373 samples, 110 (29.49 %) P. aeruginosa isolates were from admitted patients in different wards. 82 (74.5 %) came from non-critical units along with 28 (25.4 %) belonged to critical units. Prevalence of P. aeruginosafrom the non-critical units was detected from surgical ward 35 (42.6 %) followed by medical ward 25 (30.48 %), gynecology 15 (18.29 %) and orthopedics 7 (8.5 %). The highest prevalence of P. aeruginosa among critical areas were from Medicine Intensive Care Unit 14 (50 %) followed by Surgery Intensive Care Unit 9 (32.14 %) and Respiratory Intensive Care Unit 5 (17.85 %). All were observed as multidrug-resistant against different antibiotics. The current research facilitates estimating the occurrence of MDR strains in intensive care units. Therefore, routine investigation of antibiotic sensitivity patterns is crucial for lowering the healthcare-linked infection levels as well as antimicrobial resistance.

Article History

Received: Feb 27, 2022; Accepted: Dec 14, 2022; Published: Dec 31, 2022

Recommended Citation

Ishfaq, R., Khan, H. R., Javeed, M., Tanveer, M. I., & Ashraf, A. (2022). Prevalence and Evaluation of Multidrug Resistance Pattern of Pseudomonas Aeruginosa among Critical and Non-Critical Areas at a Tertiary Care hospital of Multan, Journal of Bioresource Management, 9 (4).