Autoimmune Response in Rabbits Injected with Rat and Rabbit Liver Ribosomes
Document Type
Article
Publication Date
8-31-1962
Abstract
Autoimmune hemolytic anemia and leukopenia, circulating autoantibodies for erythrocytes, leukocytes, and ribosomes; pathological changes in liver, spleen, heart, brain, and kidneys were produced in rabbits injected with rat or rabbit liver ribosomes. The hematologic and pathologic changes were reproduced by injection of anti-ribosomal serum into normal rabbits. The autoantibody specificity was related primarily to nucleotides and nucleosides.
Repository Citation
Dodd, M. C.,
Bigley, N. J.,
Geyer, V. B.,
McCoy, F. W.,
& Wilson, H. E.
(1962). Autoimmune Response in Rabbits Injected with Rat and Rabbit Liver Ribosomes. Science, 137 (3531), 688-689.
https://corescholar.libraries.wright.edu/ncbp/486
DOI
10.1126/science.137.3531.688
