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In 2012, 162 unintentional drug overdose deaths, the highest number on record, occurred in Montgomery County, Ohio. This finding comes from the Poisoning Death Review (PDR), a process involving the compilation and interpretation of multiple data sets from the Montgomery County Coroner’s Office. The PDR is carried out by faculty and staff at the Wright State University Boonshoft School of Medicine in collaboration with the Montgomery County Coroner’s Office. The designation of deaths being either unintentional (accident) or intentional (suicide) is made by the Montgomery County Coroner. This is the third year the PDR has been conducted. In 2011, 130 unintentional drug overdose deaths occurred in Montgomery County; 127 in 2010.