Title

DNA Ploidy of Basal Cell Carcinoma Determined by Image Cytometry of Fresh Smears

Document Type

Article

Publication Date

6-1993

Abstract

Image analysis of nuclear DNA content (DNA ploidy) was performed on smears of basal cell carcinoma (BCC) obtained during Mohs microscopically-controlled surgery from 51 tumors. DNA ploidy was compared with histologic growth pattern and the contour of the invading edge. There was a statistically significantly increased frequency of DNA aneuploidy in smears from BCC exhibiting partial or total diffuse (infiltrative and superficial multicentric) growth patterns (80%; 32 of 40) as compared to solely circumscribed growth patterns (0%; 0 of 11) (p< 0.001).

DOI

10.1111/j.1600-0560.1993.tb00646.x