The Importance of Acid Reflux Patterns in Neurologically Damaged Children Detected by Four-Channel Esophageal pH Monitoring
Multiple level esophageal pH studies were performed in 23 neurologically damaged infants and children for evaluation of gastroesophageal reflux (GER) and feeding difficulties. The patients were placed in one of three anatomic groups based on the extent of their neurologic injury. Seven children had an acute cerebral injury due to closed head trauma or infections. Six patients with perinatal asphyxia or progressive encephalopathy had a global CNS insult. Eight children with CNS malformations or intraventricular hemorrhage had subacute cerebral damage. Two patients with generalized seizure disorders could not be anatomically classified. In all groups, abnormalities detected at the distal esophagus were also noted at more proximal levels. The middle esophageal probe demonstrated a significant difference (PPPP
Ross, M. N.,
Haase, G. M.,
Reiley, T. T.,
& Meagher, D. P.
(1988). The Importance of Acid Reflux Patterns in Neurologically Damaged Children Detected by Four-Channel Esophageal pH Monitoring. Journal of Pediatric Surgery, 23 (6), 573-576.