Possible Role of the Transcription Factor Oct-3/4 in Control of Human Chorionic Gonadotropin Expression

Document Type

Book Chapter

Publication Date

1999

Abstract

During a study on the regulation of interferon-i genes in choriocarcinoma cells, an hCGa-CAT construct was included as an internal control to check transfection efficiencies. Although Oct-3/4 coexpression had little effect on expression from an IFN-ti promoter that carried several potential Oct binding sequences, the hCGa-CAT construct was strongly silenced. This serendipitous discovery led to the data reported in this chapter and two earlier papers (1,2).

DOI

10.1007/978-1-4612-1548-6_22

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