Trophoblast Interferons: Expression During Development and Gene Organization

Document Type

Conference Proceeding

Publication Date

1993

Abstract

The major proteins that are secreted by the preimplantation trophoblast of domestic ruminant species and that have been implicated as the an¬tiluteolytic factors modulating the release of the uterine luteolysin, pros¬taglandin F2a, during the period of maternal recognition of pregnancy have been identified as type I interferons (IFN). They are most appropriately named trophoblast IFN (IFNτ) and are related structurally to the IFNα, IFNβ, and IFNω with which they also share many biological properties.

DOI

10.1007/978-1-4612-2718-2_14

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