Document Type

Response or Comment

Publication Date

11-7-2016

Identifier/URL

41004481 (Pure)

Abstract

Most physiological processes are sensitive to pH (i.e., hydrogen ion activity) and regulation of pH within tissues and body fluids represents a fundamental homeostatic process in living organisms. At the organismal level, acid-base balance is achieved by fast respiratory modulations of the partial pressure of CO2 in combination with slower transepithelial ion movements to accommodate excretion and retention of bicarbonate and protons in response to acid-base disturbances. At the cellular and subcellular levels, acid-base balance is achieved by ion exchange.

Comments

This work is licensed under CC BY 4.0

© 2016 Santin, Wang, Dukkipati and Hartzler.

DOI

10.3389/fphys.2016.00513


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