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Theses/Dissertations from 2024

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Evaluation and Modulation of the Circadian Clock in Human Keratinocytes and Epidermal Skin, William Harold Cvammen IV

Theses/Dissertations from 2023

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Identifying a Novel Ferrocene Derivative as a K-Ras Inhibitor, Kristen Marie Rehl

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Friend or Foe? The Role of Transforming Growth Factor-β (TGFβ) Signaling in Calcineurin Inhibitor-Induced Renal Damage, Adaku Uwe

Theses/Dissertations from 2022

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ERK3 and DGKζ Interact to Modulate Cell Motility in Lung Cancer Cells, Amanda Myers

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FBXL16 Promotes Breast Cancer Cell Growth and Diminishes Fulvestrant Responsiveness by Stabilizing ERα Protein, Krushangi Nirav Shah

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Reciprocal Regulation of Transketolase-like 1 and Hypoxia-inducible Factor 1 Alpha in Metabolic Reprogramming and Growth of Diffuse Midline Glioma, H3 K27M-mutant, Christopher Andrew Waker

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The Role of SON in Chromatin-Mediated Gene Expression, Melissa Jordan Ward

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AhR-mediated Transcriptional Regulation of the Human Immunoglobulin Hs1.2 Enhancer, Sydney White

Theses/Dissertations from 2021

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The Regulation of Small GTPase Rac1 Phosphorylation, Activation and Subcellular Localization by ΔNp63α, Amjad Ahmed Aljagthmi

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NMR Metabolomics for Optimizing Cell-Free Protein Synthesis, Angela M. Campo

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ALS-induced Excitability Changes in Individual Motorneurons and the Spinal Motorneuron Network in SOD1-G93A Mice at Symptom Onset, Christiana S.I. Draper

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Modeling of Excitation in Skeletal Muscle, Sabrina Kinzie Metzger

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Altered Skeletal Muscle Excitation-Contraction Coupling in the R6/2 Transgenic Mouse Model for Huntington's Disease, Daniel R. Miranda

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Altered Skeletal Muscle Excitation-Contraction Coupling in the R6/2 Transgenic Mouse Model for Huntington's Disease, Daniel R. Miranda

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Carbon Nanotube-Coated Scaffolds for Tissue Engineering Applications, Soham Dipakbhai Parikh

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Acute Oxygen-Sensing by the Carotid Bodies : The Thermal Microdomain Model, Ryan Joseph Rakoczy

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Alterations in Cardiac Motions of the Failing Heart during Direct Mechanical Ventricular Actuation, Benjamin Allyn Schmitt

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Augmenting Structure/Function Relationship Analysis with Deep Learning for the Classification of Psychoactive Drug Activity at Class A G Protein-Coupled Receptors, Hannah Willow Shows

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Augmenting Structure/Function Relationship Analysis with Deep Learning for the Classification of Psychoactive Drug Activity at Class A G Protein-Coupled Receptors, Hannah Willow Shows

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Multi-Label Classification on Locally-Linear Data: Application to Chemical Toxicity Prediction, Xiu Huan Yap

Theses/Dissertations from 2020

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Global Identification of Human Modifier Genes of Alpha-synuclein Toxicity, Ishita Haider

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Ultraviolet-B Radiation Induces Release of Bioactive Microvesicle Particles in Keratinocytes via Platelet-Activating Factor and Acid Sphingomyelinase, Langni Liu

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RENCA Macrobeads Inhibit Tumor Cell Growth via EGFR Activation and Regulation of MEF2 Isoform Expression, Prithy Caroline Martis

Theses/Dissertations from 2019

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Differential microRNA Expression in Barrett's Esophagus correlates with regulation of Posterior Homeotic Genes, Reilly June Clark

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Biomarker-Performance Associations During Nutritional and Exercise Intervention in Air Force Personnel, Jennifer Jurcsisn

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Mitochondria-Dependent Cellular Toxicity of α-synuclein Modeled in Yeast, Rajalakshmi Santhanakrishnan

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Type 2 Diabetes Leads to Impairment of Cognitive Flexibility and Disruption of Excitable Axonal Domains in the Brain, Leonid M. Yermakov

Theses/Dissertations from 2018

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A Novel Approach for Cancer Characterization Using Latent Dirichlet Allocation and Disease-Specific Genomic Analysis, Hima Bindu Yalamanchili

Theses/Dissertations from 2017

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Identification of Novel Ligands and Structural Requirements for Heterodimerization of the Liver X Receptor Alpha, Shimpi Bedi

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Dysregulation of Phospholipase D (PLD) isoforms increases breast cancer cell invasion, Kristen Fite

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Functions of the Apical Na+/ K+/ 2cl- Cotransporter 1 in Choroid Plexus Epithelial Cells, Jeannine Marie Crum Gregoriades

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Functions of the apical Na+/ K+/ 2Cl- Cotransporter 1 in choroid plexus epithelial cells., Jeannine Marie Crum Gregoriades

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Persistent Inward Currents Play a Role in Muscle Dysfunction Seen in Myotonia Congenita, Ahmed Alaa Hawash

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Persistent Inward Currents Play a Role in Muscle Dysfunction Seen in Myotonia Congenita, Ahmed Alaa Hawash

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A novel system for detection of DNA double strand breaks and repair in human cells, Todd Warren Lewis

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Antimicrobial Activity of Fractionated Borohydride-Capped and Electrochemical Colloidal Silver, Marjorie M. Markopoulos

Novel Mechanisms Underlying Warm-up and Percussion Myotonia in Myotonia Congenita, Kevin Richard NNovak

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Analytical-based methodologies to examine In vitro nanokinetics of silver nanoparticles, Sesha Lakshmi Arathi Paluri

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Context-dependence of physiological systems: environment-physiology interactions in the respiratory control system, Joseph M. Santin

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Sensorimotor Deficits Following Oxaliplatin Chemotherapy, Jacob Adam Vincent

Theses/Dissertations from 2016

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Modeling Effects of Diet on Human Gut Microbiota, Richard Thomas Agans

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Novel therapeutic approach for regulating the susceptibility of epitheliato adenovirus infection, Mahmoud Soliman Salem Alghamri

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The Role of Interleukin-2 in Directing Vascular Smooth Muscle Cell Function and its Implications for Understanding the Progression of Atherosclerosis, Prakash Arumugam

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Interaction of DUE-B and Treslin during the initiation of DNA replication, Sumeet Poudel

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Refining a Post-Stroke Pharmacological and Physical Treatment to Reduce Infarct Volume or Improve Functional Recovery, using Gene Expression Changes in the Peri-Infarct Region to Examine Potential Mechanisms in Male and Female Rats, Moner A. Ragas

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Extension of Multivariate Analyses to the Field of Microbial Ecology, Vijay Shankar

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Evidence That Myo-Inositol Plus Ethanolamine Elevates Plasmalogen Levels And Lends Protection Against Oxidative Stress In Neuro-2A Cells, Isaie Sibomana

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Novel Cell Killing Mechanism of Hydroxyurea in the Fission Yeast Schizosaccharomyces pombe and Its Implications in Improving Antifungal Therapy, Amanpreet Singh

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A FUNCTIONAL ANALYSIS OF THE 3’ REGULATORY REGION OF THE IMMUNOGLOBULIN HEAVY CHAIN GENE, Andrew David Snyder

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Co-Transplantation of Endothelial Progenitor Cells and Neural Progenitor Cells for Treating Ischemic Stroke in a Mouse Model, Jinju Wang

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Modification Reactivity Analysis of Human Replication Protein a in Biologically Important States, Ryan James Yoakum

Theses/Dissertations from 2015

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A Novel Function for FANCJ Helicase In Microsatellite Stabilization During Replication Stress, Joanna Barthelemy

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Regulation of Motoneuron Firing Properties: Intrinsic and Circuit-Based Mechanisms, Adam S. Deardorff

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Silver Nanoparticles: the Immediate Benefits of Low Bacterial Resistance and the Long-Term Risk of Persistent Stress In Mammalian Cells, David Harold Ellis

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Vitamin D Receptor and 1α, 25-Dihydroxyvitamin D3 Mediated Regulation of ΔNp63α, Hill Tremayne Natasha

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Manipulation of Gold Nanorod Physicochemical Properties to Enhance Biocompatibility, Uptake and Intracellular Preservation of Optical Properties for Bio-Imaging and Plasmonic Photo-Therapeutic Applications, Anthony B. Polito

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The Organization of Kv2.1 Channel Proteins in the Membrane of Spinal Motoneurons: Regulation by Injury and Cellular Activity, Shannon Hunt Romer

Theses/Dissertations from 2014

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The Role of Subunit III in the Functional and Structural Regulation of Cytochrome c Oxidase in Rhodobacter spheroids, Khadijeh Salim Alnajjar

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Rab3A as a Modulator of Homeostatic Synaptic Plasticity, Andrew G. Koesters

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The Regulation of the Eight-Exon Isoform of the Coxsackievirus and Adenovirus Receptor (CAREX8) and Its Biological Relevance, Poornima Kotha Lakshmi Narayan

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Peroxisome Proliferator-Activated Receptor Alpha: Insight into the Structure, Function and Energy Homeostasis, Dhawal P. Oswal

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Apelin Regulation of K-Cl Cotransport in Vascular Smooth Muscle Cells., Neelima Sharma

Theses/Dissertations from 2013

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Differential Regulation of the Hippocampal Taurine Transporter Protein in Rat Brain: Mechanisms Contributing to Neuronal Volume Regulation, Amanda Noelle Freeman

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A Comprehensive Tool and Analytical Pathway for Differential Molecular Profiling and Biomarker Discovery, Claude Curtis Grigsby

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New Insights into the Spinal Recurrent Inhibitory Pathway Normally and After Motoneuron Regeneration, Ahmed Zayed Obeidat

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Reactive Oxygen Modulates B Lymphocyte Function via the NFκB/Rel Pathway, Eric J. Romer

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Simulating Hemodynamics in In Vitro Culture Models: Implications on Nano-Biointeractions, Monita Sharma

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The Molecular Genetics Learning Progressions: Revisions and Refinements Based on Empirical Testing in Three 10th Grade Classrooms, Amber Nicole Todd

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Elucidating a Role of Btf and TRAP150 in pre-mRNA Processing and Cell Cycle Progression, Sapna N. Varia

Theses/Dissertations from 2012

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Regulation of The DNA Unwinding Element Binding Protein DUE-B in The Cell, Yanzhe Gao

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Limitations of Functional Recovery of Stretch Reflex Circuitry After Peripheral Nerve Regeneration, Gabrielle Marie Horstman

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The Role of Ca2+ in Central Respiratory Control Neurons of the Locus Coeruleus: Development of the Chemosensitive Brake, Ann Nicole Imber

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The Role of AMP-Activated Protein Kinase (AMPK) in Hypoxic Chemotransduction by the Carotid Body, Heidi Lynn Jordan

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Regulation of the Transcription and Subcellular Localization of the Tumor Suppressor PTEN by ΔNp63α, Mary Kathryn Leonard

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'Omic' Evaluation of the Region Specific Changes Induced by Non-Cholinergic Diisopropylfluorophosphate (DFP) Exposure in Fischer 344 Rat Brain, Deirdre A. Mahle

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A Mechanism-Based Model to Describe GABAA Receptor Trafficking and Benzodiazepine Pharmacoresistance during Status Epilepticus, Elaine Alice Merrill

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Applications of Capillary Electrophoresis for Studying Serum Albumin Enantioselection of D,L-Tryptophan Analogs, Jelynn A. Stinson

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The Role of Angiotensin Converting Enzyme (ACE) 2 in a Murine Model of Insulin Resistance and Albuminuria, Nathan Michael Weir

Theses/Dissertations from 2011

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V1-Derived Renshaw Cells and IA Inhibitory Interneurons Differentiate Early During Development, Ana Benito González

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Aberrant DNA Replication at an Ectopic Chromosomal Site in Human Cells, Xiaomi Chen

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The Molecular Basis of the Interaction Between the Coxsackievirus and Adenovirus Receptor (CAR) and MAGI-1, Abimbola Olayinka Kolawole

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Impact of Insulin Resistance on Behavioral and Neurochemical Deficits in db/db Mice, Ajaykumar Narayan Sharma

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Son is Essential for Nuclear Speckle Organization, Cell Cycle Progression and Pre-mRNA Splicing, Alok S. Sharma

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A Computational Tool for Biomolecular Structure Analysis Based on Chemical and Enzymatic Modification of Native Proteins, Deacon John Sweeney

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The Development of Silver Nanoparticles as Antiviral Agents, John Christopher Trefry

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Quantitative Computed-Tomography Based Bone-Strength Indicators for the Identification of Low Bone-Strength Individuals in a Clinical Environment, Bino Abel Varghese

Theses/Dissertations from 2010

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Cytochrome C Oxidase from Rhodobacter Sphaeroides: Oligomeric Structure in the Phospholipid Bilayer and the Structural and Functional Effects of a C-Terminal Truncation in Subunit III, Teresa L. Cvetkov

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Extent and Effects of Selection to Reduce Synthetic Cost of Highly Expressed Proteins, Esley Marvin Heizer Jr

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Understanding the Molecular Dynamics of YPEL3 and FHIT Gene Expression, Kevin Daniel Kelley

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Induction of p53 Dependent Cellular Senescence Through HdmX Inhibition or YPEL3 Expression, Kelly Lynn Robbins Miller

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Cellular Effects of Replicating a Polypurine-Polypyrimidine Sequence and the Interactions of DUE-B with Replication Proteins, Shere Lynne Myers

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Charaterization of Chlorpyrifos Toxicity on the Pancreatic Beta Cell Line RINm5f, Zhongyu Yan

Theses/Dissertations from 2009

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Genetic Differentiation in Ambystomatid Salamanders Across a Fragmented Landscape, Joseph E. Bartoszek

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Cellular Function of the Ia-motoneuron Circuit Following Peripheral Nerve Regeneration, Katie Leigh Bullinger

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Ion Transport Mechanisms during Hyposmotic Regulatory and Isosmotic Apoptotic Volume Decreases in a Human Lens Epithelial Cells Line, Ameet Ajit Chimote

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Small Conductance Calcium-activated Potassium (SK) Channels in Mammalian Spinal Motoneurons, Zhihui Deng

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Induction of SOCS-1 in HSV-1-Infected Murine Keratinocytes: A Mechanism of Inhibition of Interferon Gamma, Kenneth Gene Frey

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Differential Regulation of Vitamin D Receptor (VDR) By P53, P63 and P73, Ramakrishna Kommagani

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HIF-1 Alpha: A Master Regulator of Trophoblast Differentiation and Placental Development, Kashmira Kulkarni

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Central Mechanisms Regulating Pituitary-Adrenal Activity in Infant Guinea Pigs (Cavia porcellus) during Exposure to Psychological Stressors: Independent and Combined Effects of Maternal Separation and Novelty, Deborah Suzanne Maken