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Theses/Dissertations from 2025

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The Impact of AhR and hs1.2 Enhancer Genetic Variations on IgH Expression and Antibody Production in Human B Cells, Mili Santosh Bhakta-Yadav

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Enhanced Diagnostics and Surveillance of Enteroviruses Including Serotypes Associated with Acute Flaccid Myelitis, Denise Lynette Kramer

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The Role of TRPM7 in Mouse Development and Immune Cell Function, Jananie Rockwood

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Vagus Nerve Stimulation Ameliorates Cognitive Impairment Caused by Hypoxia, Birendra Sharma

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Induced Reduction of N-glycosylation Leads to Heart Failure, Anthony M. Young

Theses/Dissertations from 2024

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Potential Role of TTT Complex in Regulating DNA Replication Checkpoint in the Fission Yeast Schizosaccharomyces pombe, Sankhadip Bhadra

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Evaluation and Modulation of the Circadian Clock in Human Keratinocytes and Epidermal Skin, William Harold Cvammen IV

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Insights into Hyperkalemic Periodic Paralysis: Novel Mechanisms and Treatments, Christopher Dupont

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A Novel In-vitro Approach to Investigate the Molecular Interaction Between Inhaled Particles and the Human Pulmonary Surfactant System, Bryan Mayville

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Novel Approaches to Treatment of Hyperexcitability in Skeletal Muscle, Phillip Vance Walker II

Theses/Dissertations from 2023

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DNA Instability at (ATTCT) Microsatellites in Human Cells, Venicia Alhawach

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Lipin1 Overexpression Ameliorates the Dystrophic Phenotype in MDX Mice by Enhancing Myofiber Membrane Integrity, Abdullah Alshudukhi

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Microsatellite Induced Genomic Instability and Mutagenesis Through Break Induced Replication, Rujuta Yashodhan Gadgil

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Lipin1 Improves Membrane Integrity in Dystrophic Muscles of MDX Mice, Abdulrahman Jama

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Calpains in the Peripheral Nerve and during Demyelination and Degeneration in Rodents, John A. Miller

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Identifying a Novel Ferrocene Derivative as a K-Ras Inhibitor, Kristen Marie Rehl

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Unfolding the Link Between the Axon Initial Segment, Endoplasmic Reticulum Stress, and Cognitive Impairment in Type 2 Diabetes, Jennae Shelby

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Friend or Foe? The Role of Transforming Growth Factor-β (TGFβ) Signaling in Calcineurin Inhibitor-Induced Renal Damage, Adaku Uwe

Theses/Dissertations from 2022

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ERK3 and DGKζ Interact to Modulate Cell Motility in Lung Cancer Cells, Amanda Myers

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FBXL16 Promotes Breast Cancer Cell Growth and Diminishes Fulvestrant Responsiveness by Stabilizing ERα Protein, Krushangi Nirav Shah

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Reciprocal Regulation of Transketolase-like 1 and Hypoxia-inducible Factor 1 Alpha in Metabolic Reprogramming and Growth of Diffuse Midline Glioma, H3 K27M-mutant, Christopher Andrew Waker

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The Role of SON in Chromatin-Mediated Gene Expression, Melissa Jordan Ward

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AhR-mediated Transcriptional Regulation of the Human Immunoglobulin Hs1.2 Enhancer, Sydney White

Theses/Dissertations from 2021

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The Regulation of Small GTPase Rac1 Phosphorylation, Activation and Subcellular Localization by ΔNp63α, Amjad Ahmed Aljagthmi

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NMR Metabolomics for Optimizing Cell-Free Protein Synthesis, Angela M. Campo

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ALS-induced Excitability Changes in Individual Motorneurons and the Spinal Motorneuron Network in SOD1-G93A Mice at Symptom Onset, Christiana S.I. Draper

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Modeling of Excitation in Skeletal Muscle, Sabrina Kinzie Metzger

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Altered Skeletal Muscle Excitation-Contraction Coupling in the R6/2 Transgenic Mouse Model for Huntington's Disease, Daniel R. Miranda

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Altered Skeletal Muscle Excitation-Contraction Coupling in the R6/2 Transgenic Mouse Model for Huntington's Disease, Daniel R. Miranda

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Carbon Nanotube-Coated Scaffolds for Tissue Engineering Applications, Soham Dipakbhai Parikh

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Acute Oxygen-Sensing by the Carotid Bodies : The Thermal Microdomain Model, Ryan Joseph Rakoczy

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Alterations in Cardiac Motions of the Failing Heart during Direct Mechanical Ventricular Actuation, Benjamin Allyn Schmitt

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Augmenting Structure/Function Relationship Analysis with Deep Learning for the Classification of Psychoactive Drug Activity at Class A G Protein-Coupled Receptors, Hannah Willow Shows

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Augmenting Structure/Function Relationship Analysis with Deep Learning for the Classification of Psychoactive Drug Activity at Class A G Protein-Coupled Receptors, Hannah Willow Shows

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Multi-Label Classification on Locally-Linear Data: Application to Chemical Toxicity Prediction, Xiu Huan Yap

Theses/Dissertations from 2020

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Global Identification of Human Modifier Genes of Alpha-synuclein Toxicity, Ishita Haider

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Ultraviolet-B Radiation Induces Release of Bioactive Microvesicle Particles in Keratinocytes via Platelet-Activating Factor and Acid Sphingomyelinase, Langni Liu

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RENCA Macrobeads Inhibit Tumor Cell Growth via EGFR Activation and Regulation of MEF2 Isoform Expression, Prithy Caroline Martis

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Host-Parasite Interactions: Comparative Analyses of Population Genomics, Disease-Associated Genomic Regions, and Host Use, Sara Rose Seibert

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Regulation of ΔNp63α by TIP60 Promotes Cellular Proliferation, Andrew Jared Stacy

Theses/Dissertations from 2019

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Differential microRNA Expression in Barrett's Esophagus correlates with regulation of Posterior Homeotic Genes, Reilly June Clark

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Rescue of ALS Protein FUS Toxicity by TAF, Elliott Hayden

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Biomarker-Performance Associations During Nutritional and Exercise Intervention in Air Force Personnel, Jennifer Jurcsisn

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Adenovirus Co-opts Neutrophilic Inflammation in Order to Enhance Entry into Epithelial Cells, James Matthew Readler

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Mitochondria-Dependent Cellular Toxicity of α-synuclein Modeled in Yeast, Rajalakshmi Santhanakrishnan

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Type 2 Diabetes Leads to Impairment of Cognitive Flexibility and Disruption of Excitable Axonal Domains in the Brain, Leonid M. Yermakov

Theses/Dissertations from 2018

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Consequences of TRPM7 Kinase Inactivation in Immune Cells, Pavani Beesetty

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The Pattern of Sensory Axonal Endings Together with Synaptic Transmission Influence the Development of Proprioceptive Circuits in the Spinal Cord, Yiyun Dai

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Regulation of the Motor Output of the Spinal Cord: Burst Firing Generation and Sensorimotor Integration, Amr A. Mahrous

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A Novel Approach for Cancer Characterization Using Latent Dirichlet Allocation and Disease-Specific Genomic Analysis, Hima Bindu Yalamanchili

Theses/Dissertations from 2017

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Glycolytic Metabolism and Pregnancy Parameters in the Murine Placenta, Renee Elizabeth Albers

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Identification of Novel Ligands and Structural Requirements for Heterodimerization of the Liver X Receptor Alpha, Shimpi Bedi

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Proteomic Analysis of Ischemic Stroke Blood Biomarkers, April Arnold Daubenspeck

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Regulation of the Expression and Activity of Extracellular Signal-Regulated Kinase 3 (ERK3), Lobna Elkhadragy

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Dysregulation of Phospholipase D (PLD) isoforms increases breast cancer cell invasion, Kristen Fite

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Phospholipase D: Key Player in Macrophage-Mediated Inflammation and Resolution, Ramya Ganesan

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Functions of the Apical Na+/ K+/ 2cl- Cotransporter 1 in Choroid Plexus Epithelial Cells, Jeannine Marie Crum Gregoriades

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Functions of the apical Na+/ K+/ 2Cl- Cotransporter 1 in choroid plexus epithelial cells., Jeannine Marie Crum Gregoriades

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Persistent Inward Currents Play a Role in Muscle Dysfunction Seen in Myotonia Congenita, Ahmed Alaa Hawash

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Persistent Inward Currents Play a Role in Muscle Dysfunction Seen in Myotonia Congenita, Ahmed Alaa Hawash

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A novel system for detection of DNA double strand breaks and repair in human cells, Todd Warren Lewis

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Making Meaning: Shifts in Meaningfulness Across Three Modeling Units, Jeannette Manger

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Antimicrobial Activity of Fractionated Borohydride-Capped and Electrochemical Colloidal Silver, Marjorie M. Markopoulos

Novel Mechanisms Underlying Warm-up and Percussion Myotonia in Myotonia Congenita, Kevin Richard NNovak

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Analytical-based methodologies to examine In vitro nanokinetics of silver nanoparticles, Sesha Lakshmi Arathi Paluri

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Context-dependence of physiological systems: environment-physiology interactions in the respiratory control system, Joseph M. Santin

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Sensorimotor Deficits Following Oxaliplatin Chemotherapy, Jacob Adam Vincent

Theses/Dissertations from 2016

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Modeling Effects of Diet on Human Gut Microbiota, Richard Thomas Agans

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Novel therapeutic approach for regulating the susceptibility of epitheliato adenovirus infection, Mahmoud Soliman Salem Alghamri

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The Role of Interleukin-2 in Directing Vascular Smooth Muscle Cell Function and its Implications for Understanding the Progression of Atherosclerosis, Prakash Arumugam

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Interaction of DUE-B and Treslin during the initiation of DNA replication, Sumeet Poudel

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Refining a Post-Stroke Pharmacological and Physical Treatment to Reduce Infarct Volume or Improve Functional Recovery, using Gene Expression Changes in the Peri-Infarct Region to Examine Potential Mechanisms in Male and Female Rats, Moner A. Ragas

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Extension of Multivariate Analyses to the Field of Microbial Ecology, Vijay Shankar

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Evidence That Myo-Inositol Plus Ethanolamine Elevates Plasmalogen Levels And Lends Protection Against Oxidative Stress In Neuro-2A Cells, Isaie Sibomana

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Novel Cell Killing Mechanism of Hydroxyurea in the Fission Yeast Schizosaccharomyces pombe and Its Implications in Improving Antifungal Therapy, Amanpreet Singh

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A FUNCTIONAL ANALYSIS OF THE 3’ REGULATORY REGION OF THE IMMUNOGLOBULIN HEAVY CHAIN GENE, Andrew David Snyder

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Co-Transplantation of Endothelial Progenitor Cells and Neural Progenitor Cells for Treating Ischemic Stroke in a Mouse Model, Jinju Wang

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Modification Reactivity Analysis of Human Replication Protein a in Biologically Important States, Ryan James Yoakum

Theses/Dissertations from 2015

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A Novel Function for FANCJ Helicase In Microsatellite Stabilization During Replication Stress, Joanna Barthelemy

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Regulation of Motoneuron Firing Properties: Intrinsic and Circuit-Based Mechanisms, Adam S. Deardorff

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Silver Nanoparticles: the Immediate Benefits of Low Bacterial Resistance and the Long-Term Risk of Persistent Stress In Mammalian Cells, David Harold Ellis

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Vitamin D Receptor and 1α, 25-Dihydroxyvitamin D3 Mediated Regulation of ΔNp63α, Hill Tremayne Natasha

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Manipulation of Gold Nanorod Physicochemical Properties to Enhance Biocompatibility, Uptake and Intracellular Preservation of Optical Properties for Bio-Imaging and Plasmonic Photo-Therapeutic Applications, Anthony B. Polito

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Measuring the Acute Physiological Effects of Leptin in the Carotid Body, Richard Laurence Pye

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The Organization of Kv2.1 Channel Proteins in the Membrane of Spinal Motoneurons: Regulation by Injury and Cellular Activity, Shannon Hunt Romer

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The Guinea Pig Model For Organophosphate Toxicology and Therapeutic Development, Christopher Daniel Ruark

Theses/Dissertations from 2014

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The Role of Subunit III in the Functional and Structural Regulation of Cytochrome c Oxidase in Rhodobacter spheroids, Khadijeh Salim Alnajjar

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Chemosensitive Neurons of the Locus Coeruleus and the Nucleus Tractus Solitarius: Three Dimensional Morphology and Association with the Vasculature, Cathy D. Graham

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Rab3A as a Modulator of Homeostatic Synaptic Plasticity, Andrew G. Koesters

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The Regulation of the Eight-Exon Isoform of the Coxsackievirus and Adenovirus Receptor (CAREX8) and Its Biological Relevance, Poornima Kotha Lakshmi Narayan

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Guanine Nucleotide Exchange Activity of Phospholipase D2 and its Regulation, Madhupriya Mahankali

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Peroxisome Proliferator-Activated Receptor Alpha: Insight into the Structure, Function and Energy Homeostasis, Dhawal P. Oswal

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Apelin Regulation of K-Cl Cotransport in Vascular Smooth Muscle Cells., Neelima Sharma

Theses/Dissertations from 2013

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Differential Regulation of the Hippocampal Taurine Transporter Protein in Rat Brain: Mechanisms Contributing to Neuronal Volume Regulation, Amanda Noelle Freeman

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A Comprehensive Tool and Analytical Pathway for Differential Molecular Profiling and Biomarker Discovery, Claude Curtis Grigsby

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New Insights into the Spinal Recurrent Inhibitory Pathway Normally and After Motoneuron Regeneration, Ahmed Zayed Obeidat

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Reactive Oxygen Modulates B Lymphocyte Function via the NFκB/Rel Pathway, Eric J. Romer

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Simulating Hemodynamics in In Vitro Culture Models: Implications on Nano-Biointeractions, Monita Sharma

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The Molecular Genetics Learning Progressions: Revisions and Refinements Based on Empirical Testing in Three 10th Grade Classrooms, Amber Nicole Todd

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Elucidating a Role of Btf and TRAP150 in pre-mRNA Processing and Cell Cycle Progression, Sapna N. Varia