Respiration in Primary Cultured Cerebellar Granule Neurons and Cerebral Cortical Neurons
Document Type
Article
Publication Date
2-1-1984
Find this in a Library
Abstract
Respiration was measured polarographically in primary cultures enriched with cerebellar granule neurons or cerebral cortical neurons. The basal respiratory rate, measured on the sixth day after culturing, was 12.00 natom equiv. O/mg protein/min for the cortical neurons and 12.70 natom equiv. O/mg protein/min for the granule neurons. Maximal stimulation by 2,4-dinitrophenol produced a 20–40% increase over the basal rate for both neuronal types. Oligomycin inhibited neuronal basal respiration by 45%. These respiratory rates in neurons from primary culture are markedly lower than those measured in astrocytes grown under similar conditions.
Repository Citation
Jameson, N.,
Olson, J. E.,
Nguyen, H.,
& Holtzman, D.
(1984). Respiration in Primary Cultured Cerebellar Granule Neurons and Cerebral Cortical Neurons. Journal of Neurochemistry, 42 (2), 470-474.
https://corescholar.libraries.wright.edu/emergency_medicine/274
DOI
10.1111/j.1471-4159.1984.tb02701.x
