Hyperthermia-Induced Seizures in the Rat Pup: A Model for Febrile Convulsions in Children
Document Type
Article
Publication Date
1981
Abstract
Seizures were produced in rat pups by ambient hyperthermia. Seizure threshold temperatures, measured rectally and intracerebrally, increased between 2 and 10 days of age. Electrocortical paroxysmal discharges were confirmed in hyperthermic 6- and 10-day-old pups. The increasing resistance to hyperthermic seizures with maturation and the electroencephalographic changes induced by hyperthermia are similar to those in young children.
Repository Citation
Holtzman, D.,
Obana, K.,
& Olson, J. E.
(1981). Hyperthermia-Induced Seizures in the Rat Pup: A Model for Febrile Convulsions in Children. Science, 213 (4511), 1034-1036.
https://corescholar.libraries.wright.edu/emergency_medicine/284
DOI
10.1126/science.7268407
