Publication Date


Document Type


Committee Members

Athanasios Bubulya (Committee Member), B. Laurel Elder (Committee Member), Barbara Hull (Advisor)

Degree Name

Master of Science (MS)


Actinobacteria, one phylum of gram positive bacteria, are found throughout all the environments on earth. Actinobacteria have long been studied for the benefits they provide, both to their environment and to humans, and have a great capacity for adaptation and evolution. They decompose organic matter, replenishing nutrients into the soil, and as such are important members of the food chain. Humans benefit from the exploitation of Actinobacterial metabolites as antimicrobial drugs. These antimicrobials have been effectively utilized for decades in the fight against infectious disease. Despite the success of this drug arsenal we are now in the midst of an epidemic of multidrug-resistant superbugs that render established drugs ineffective. In order to find new antimicrobial drugs, researchers have turned to the recent discovery of several new species of marine Actinobacteria and analyzed their metabolites for antimicrobial activity. Several metabolites were effective in vitro, and may lead to the development of marketable pharmaceuticals.

Page Count


Department or Program

Department of Biological Sciences

Year Degree Awarded


Included in

Biology Commons