A Comparison of Codon Usage Trends in Prokaryotes

Authors

Amanda L. Hanes, Wright State University - Main Campus
Michael L. Raymer, Wright State University - Main CampusFollow
Travis E. Doom, Wright State University - Main CampusFollow
Dan E. Krane, Wright State University - Main CampusFollow

Document Type

Conference Proceeding

Publication Date

6-2009

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Abstract

Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms’ lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism’s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.

Comments

Presented at the Ohio Collaborative Conference on Bioinformatics (OCCBIO), Cleveland, OH, June 15-17, 2009.

Repository Citation

Hanes, A. L., Raymer, M. L., Doom, T. E., & Krane, D. E. (2009). A Comparison of Codon Usage Trends in Prokaryotes. Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009, 83-86.
https://corescholar.libraries.wright.edu/knoesis/531

DOI

10.1109/OCCBIO.2009.26