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The LSDIS Lab advances the field of distributed information systems by researching semantic techniques for exploiting heterogeneous multimedia information and improving processes, encompassing the central promise of the Semantic Web initiative. It is pursuing cutting edge research in ontology development for demanding scientific domains, semantic heterogeneity and integration, complex relationships discovery and semantic analytics, and Semantic Web services and processes. Past work of the LSDIS lab can be characterized by keywords: semantic interoperability, syntactic and semantic metadata for text and digital media, metadata based integration of Web content, ontology-driven information systems, multi-ontology query processing, transactional workflows and workflow management. Significant past projects include InfoHarness/VisualHaness, InfoQuilt, OBSERVER, and METEOR.