Assessing the Implications for Close Relatives in the Event of Similar but Nonmatching DNA Profiles

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Winter 2006

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A complete match between the STR DNA profile of an evidence sample and that of an individual included in a database of profiles of convicted offenders has clear utility as an investigative tool. Very similar but nonetheless nonmatching DNA profiles also can provide useful information by suggesting that a close relative of the individual may be the source of the evidence sample. This article describes a general framework for determining the relative likelihood that an individual’s close relative is the source of an imperfectly matching DNA profile.

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