Neonates and Medicines: A Roadmap to Further Improve Neonatal Pharmaceutical Care
Document Type
Editorial
Publication Date
6-2016
Abstract
The treatment of newborns with safe and effective medicines is of critical importance for their outcome and subsequent quality of life. Despite this, it is still a common practice to prescribe medicines to neonates outside the label, extrapolating from dosing regimens and indications validated in older populations and based on non-neonatal pathophysiology. In a recent meta-analysis (2015) evaluating 829 (1994–2012) studies on prescribing practices in pediatric hospital care, off-label and unlicensed medicines prescriptions ranged from 12 to 71 % and 0.2 to 48 %. These authors hereby reconfirmed that (pre)term neonates were still most commonly exposed to off-label and unlicensed medicines [12].
Repository Citation
Allegaert, K.,
& Sherwin, C. M.
(2016). Neonates and Medicines: A Roadmap to Further Improve Neonatal Pharmaceutical Care. European Journal of Pediatrics, 175 (6), 743-746.
https://corescholar.libraries.wright.edu/pediatrics/234
DOI
10.1007/s00431-015-2686-2
