Therapeutic Drug Monitoring in Pregnancy
Document Type
Book Chapter
Publication Date
2016
Abstract
During pregnancy, important physiologic changes occur that affect pharmacokinetics and ultimately drug management. These include changes to renal and liver function, changes in serum protein levels, and the addition of a pharmacokinetic compartment (the infant and placenta) that is not present in the broader population. In addition, postpartum return to baseline physiology can further complicate drug management. This chapter examines therapeutic drug monitoring issues associated with pregnancy, including specific examples such as management of antidepressants.
Repository Citation
Campbell, S. C.,
Salisbury, L. M.,
Roberts, J. K.,
Kamyar, M.,
Fredrickson, J.,
Constantine, M. M.,
& Sherwin, C. M.
(2016). Therapeutic Drug Monitoring in Pregnancy. Clinical Challenges in Therapeutic Drug Monitoring, 185-211.
https://corescholar.libraries.wright.edu/pediatrics/342
