Evolution of Antiglomerular Basement Membrane Glomerulonephritis into Membranous Glomerulonephritis

Document Type

Article

Publication Date

11-13-2007

Abstract

Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare disease characterized by autoantibodies to the alpha 3 chain of type IV collagen in the GBM. It is also known as Goodpasture’s syndrome when associated with pulmonary hemorrhage due to autoantibodies to the alpha 3 chain of type IV collagen also present in pulmonary alveoli. Even more rare is the evolution of anti-GBM GN into membranous nephropathy(MN). We report the management of a 9-year-old Caucasian girl with anti-GBM GN that evolved into MN and briefly review the literature

DOI

10.1007/s00467-007-0639-3

PMCID

17999092

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