Fish Odor Syndrome: A Case Report of Trimethylaminuria

Authors

Catherine A. Ulman
Julian J. Trevino, Wright State UniversityFollow
Marvin E. Miller, Wright State UniversityFollow
Rishi K. Gandhi, Wright State UniversityFollow

Document Type

Letter to the Editor

Publication Date

1-2014

Abstract

Trimethylaminuria is a rare, autosomal recessive, metabolic disorder that results in accumulation of trimethylamine (TMA), which smells like rotten fish. The chemical is excreted in sweat and urine owing to a deficiency in the enzyme flavin monooxygenase 3 (FMO3). We report a case of trimethylaminuria in a 12-year-old girl. The patient failed treatment with diet and hygiene modification, but achieved symptomatic improvement after a four-month course of metronidazole.

Comments

Copyright 2014 by the article author(s). This work is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs4.0 license.

Repository Citation

Ulman, C. A., Trevino, J. J., Miller, M. E., & Gandhi, R. K. (2014). Fish Odor Syndrome: A Case Report of Trimethylaminuria. Dermatology Online Journal, 20 (1).
https://corescholar.libraries.wright.edu/pediatrics/78