THz Medical Imaging: in vivo Hydration Sensing
Document Type
Article
Publication Date
9-1-2011
Identifier/URL
40224410 (Pure); 80052493616 (QABO); 26085958 (PubMed); PMC4467694 (PubMedCentral)
Abstract
The application of THz to medical imaging is experiencing a surge in both interest and federal funding. A brief overview of the field is provided along with promising and emerging applications and ongoing research. THz imaging phenomenology is discussed and tradeoffs are identified. A THz medical imaging system, operating at ∼ 525 GHz center frequency with ∼125 GHz of response normalized bandwidth is introduced and details regarding principles of operation are provided. Two promising medical applications of THz imaging are presented: skin burns and cornea. For burns, images of second degree, partial thickness burns were obtained in rat models in vivo over an 8 hour period. These images clearly show the formation and progression of edema in and around the burn wound area. For cornea, experimental data measuring the hydration of ex vivo porcine cornea under drying is presented demonstrating utility in ophthalmologic applications.
Repository Citation
Devlin, C. L.,
Vogel, F. L.,
Slater, R. H.,
Brown, E. R.,
Bunker, C. E.,
Fernando, K. A.,
& Ewing, R. L.
(2011). THz Medical Imaging: in vivo Hydration Sensing. IEEE Transactions on Terahertz Science and Technology, 1 (1), 201-219.
https://corescholar.libraries.wright.edu/physics/1227
DOI
10.1109/TTHZ.2011.2159551
