Alpha Melanocyte Stimulating Hormone Reverses Corticotropin-Releasing Hormone-Induced Sickness Behaviors in Infant Guinea Pigs

Authors

Patricia A. Schiml-Webb, Wright State University - Main CampusFollow
Terrence Deak
Emily E. Miller
Michael B. Hennessy, Wright State University - Main CampusFollow

Document Type

Conference Proceeding

Publication Date

6-2005

Abstract

Prolonged maternal separation in infant guinea pigs is associated with the reduction of active behaviors such as locomotion and distress vocalizations, and with the onset of passive behaviors, such as immobility, crouching (a species-typical hunched posture), eye closing, and piloerection. Previous research indicates that the passive responses represent stress-induced sickness behaviors mediated by a systemic inflammatory response. For instance, we have previously shown that alpha melanocyte stimulating hormone (alpha-MSH; an anti-inflammatory agent) reverses separation-induced sickness behaviors. Because the passive responses can also be induced by corticotropin-releasing hormone (CRH), here we determined whether alpha-MSH could also reverse CRH-induced passive behaviors.

Comments

Abstract of poster presented at the 9th Annual Meeting of the Society for Behavioral Neuroendocrinology, Austin, TX, June 22-25, 2005.

Repository Citation

Schiml-Webb, P. A., Deak, T., Miller, E. E., & Hennessy, M. B. (2005). Alpha Melanocyte Stimulating Hormone Reverses Corticotropin-Releasing Hormone-Induced Sickness Behaviors in Infant Guinea Pigs. Hormones and Behavior, 48 (1), 212, 126-126.
https://corescholar.libraries.wright.edu/psychology/225

DOI

10.1016/j.yhbeh.2005.03.002