Publication Date
2016
Document Type
Thesis
Committee Members
Jason Parker (Committee Member), Jaime Ramirez-Vick (Committee Member), Ulas Sunar (Advisor)
Degree Name
Master of Science in Biomedical Engineering (MSBME)
Abstract
Nearly 4 million neonates die every year due to brain injuries, most caused by hypoxia. Neonatal ICU requires newborns with critical health conditions to be monitored continuously calling for the need of a non-invasive, compact and portable device. However, commercial devices are mostly bulky and/or expensive. The neonatal mortality is higher in under-developed countries, where such expensive and large devices are not affordable. Hence, my thesis focuses on building first generation compact, inexpensive, and wireless device that can monitor and provide feedback to clinicians during intervention. This approach is based on light absorption by oxy- and deoxy-hemoglobin chromophores. The total cost of this device is less than $100, which is lower than commercial devices (>$10K). The device has SNR of 65 dB. It was successfully tested by the arm occlusion protocol, which allowed measuring real-time oxygenation changes in vivo. Overall, the first generation device shows promise for future clinical studies.
Page Count
112
Department or Program
Department of Biomedical, Industrial & Human Factors Engineering
Year Degree Awarded
2016
Copyright
Copyright 2016, some rights reserved. My ETD may be copied and distributed only for non-commercial purposes and may not be modified. All use must give me credit as the original author.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
