Publication Date
2018
Document Type
Thesis
Committee Members
Kwang-Jin Cho (Committee Member), John Paietta (Committee Member), Oleg Paliy (Advisor)
Degree Name
Master of Science (MS)
Abstract
Recent studies have increasingly established the role of gut microbiota in human health and disease. Diseases such as inflammatory bowel disease, colon cancer, cardiovascular disease and many neurological disorders have been linked to specific gut microbiota composition and disturbances. There have also been attempts in recent years to modulate gut microbial composition with the use of prebiotics and probiotics to promote healthy gut and prevent diseases. This thesis investigates whether the availability of fermentable nutrients high in fiber and antioxidants such as found in green coffee, roasted coffee, and salami infused with various prebiotics altered the composition and abundance of gut microbiota. A significant difference in the composition of microbial genera was found among samples containing fermentable nutrients compared to control. Our study also showed there is a difference in abundance of Bifidobacterium, Bacteroides and Dorea, which were the top 3 most abundant genera among salami samples. Also, there was a difference in abundance of Escherichia/Shigella, Bacteroides and Bifidobacterium, which were the top 3 abundant genera among the coffee samples.
Page Count
43
Department or Program
Department of Biochemistry and Molecular Biology
Year Degree Awarded
2018
Copyright
Copyright 2018, all rights reserved. My ETD will be available under the "Fair Use" terms of copyright law.
