Submissions from 2023
Massive Loss of Proprioceptive Ia Synapses in Rat Spinal Motoneurons after Nerve Crush Injuries in the Postnatal Period, Ariadna Arbat-Plana, Sara Bolívar, Xavier Navarro, Esther Udina, and Francisco J. Alvarez
Preservation of KCC2 Expression in Axotomized Abducens Motoneurons and Its Enhancement by VEGF, Paula M. Calvo, Rosa R. de la Cruz, Angel M. Pastor, and Francisco J. Alvarez
Fast Blue and Cholera Toxin-B Survival Guide for Alpha-Motoneurons Labeling: Less Is Better in Young B6SJL Mice, but More Is Better in Aged C57Bl/J Mice, Hasan Farid, Weston B. Gleford, Lori L. Goss, Teresa L. Garrett, and Sherif M. Elbasiouny
Loss of ETV1/ER81 in Motor Neurons Leads to Reduced Monosynaptic Inputs From Proprioceptive Sensory Neurons, David R. Ladle and Simon Hippenmeyer
Submissions from 2022
IL-10 and TGF-β Increase Connexin-43 Expression and Membrane Potential of HL-1 Cardiomyocytes Coupled with RAW 264.7 Macrophages, Cora B. Cox, Mike Castro, Thomas L. Brown, and Nancy J. Bigley
Motoneuron Excitability Dysfunction in ALS: Pseudo-Mystery or Authentic Conundrum?, Sherif M. Elbasiouny
Innovative Surgical Workshops Targeting Undergraduate, Premedical, and Medical Students, Alex Gilman and Barbara Kraszpulska
Non-Invasive Transcutaneous Spinal DC Stimulation as a Neurorehabilitation ALS Therapy in Awake G93A Mice: The First Step to Clinical Translation, Morgan M. Highlander and Sherif M. Elbasiouny
The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model, Eri Iwasawa, Farrah N. Brown, Crystal Shula, Fatima Kahn, Sang Hoon Lee, Temugin Berta, David R. Ladle, Kenneth Campbell, Francesco T. Mangano, and June Goto
Diverging from the Norm: Reevaluating What Miniature Excitatory Postsynaptic Currents Tell Us about Homeostatic Synaptic Plasticity, Andrew G. Koesters, Mark M. Rich, and Kathrin L. Engisch
Suppression of Store-operated Calcium Entry Channels and Cytokine Release by Cannabinoids, J. Ashot Kozak
The Role of Microglia in Neuroinflammation of the Spinal Cord After Peripheral Nerve Injury, Tana S. Pottorf, Travis M. Rotterman, William M. McCallum, Zoë A. Haley-Johnson, and Francisco J. Alvarez
Acute Oxygen-Sensing via Mitochondria-Generated Temperature Transients in Rat Carotid Body Type I Cells, Ryan J. Rakoczy, Clay M. Schiebrel, and Christopher N. Wyatt
Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?, Mark M. Rich, Stephen N. Housley, Paul Nardelli, Randall K. Powers, and Timothy C. Cope
TRPM7 Kinase Inactivation Results in Macrophage Alkalinization and Increased Phagocytic Activity, Jananie Rockwood, Pavani Beesetty, Taku Kaitsuka, Masayuki Matsushita, and J. Ashot Kozak
Submissions from 2021
NSAIDs Naproxen, Ibuprofen, Salicylate, and Aspirin Inhibit TRPM7 Channels by Cytosolic Acidification, Rikki Chokshi, Orville Bennett, Tetyana Zhelay, and J. Ashot Kozak
In-Silico Development and Assessment of a Kalman Filter Motor Decoder for Prosthetic Hand Control, Mai Gamal, Mohamed H. Mousa, Seif Eldawlatly, and Sherif M. Elbasiouny
Genetic Targeting of Adult Renshaw Cells Using a Calbindin 1 Destabilized Cre Allele for Intersection With Parvalbumin or Engrailed1, Alicia R. Lane, Indeara C. Cogdell, Thomas M. Jessell, Jay B. Bikoff, and Francisco J. Alvarez
TRPM7 Permeant Divalent Metal Cytotoxicity During Magnesium Depletion and Loading, Alayna A. Mellott, Jananie Rockwood, Charles T. Luu, and J. Ashot Kozak
Estimating the Effects of Slicing on the Electrophysiological Properties of Spinal Motoneurons Under Normal and Disease Conditions, Mohamed H. Mousa and Sherif M. Elbasiouny
The Mechanism Underlying Transient Weakness in Myotonia Congenita, Jessica H. Myers, Kirsten Denman, Chris DuPont, Ahmed A. Hawash, Kevin R. Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A. Voss, and Mark M. Rich
Ethanol and Opioids Do Not Act Synergistically To Depress Excitation in Carotid Body Type I Cells, Ryan J. Rakoczy, Kajal Kamra, Yoon-Jae Yi, and Christopher N. Wyatt
A Mouse Model of Huntington’s Disease Shows Altered Ultrastructure of Transverse Tubules in Skeletal Muscle Fibers, Shannon H. Romer, Sabrina Metzger, Kristiana Peraza, Matthew C. Wright, D. Scott Jobe, Long-Sheng Song, Mark M. Rich, Brent D. Foy, Robert J. Talmadge, and Andrew A. Voss
Transcranial Direct Current Stimulation Modulates Connectivity of Left Dorsolateral Prefrontal Cortex With Distributed Cortical Networks, Matthew Sherwood, Kamin Kim, Lindsey K. McIntire, R. Andy McKinley, and Charan Ranganath
Intensity-Dependent Changes in Quantified Resting Cerebral Perfusion with Multiple Sessions of Transcranial DC Stimulation, Matthew Sherwood, Lindsey McIntire, Aaron T. Madaris, Kamin Kim, Charan Ranganath, and R. Andy McKinley
Placenta-Specific Slc38a2/SNAT2 Knockdown Causes Fetal Growth Restriction in Mice, Owen R. Vaughan, Katarzyna Maksym, Elena Silva, Kenneth Barentsen, Russel V. Anthony, Sara L. Hillman, Thomas L. Brown, Rebecca Spencer, Anna L. David, Fredrick J. Rosario, Theresa L. Powell, and Thomas Jansson
Current State of Preeclampsia Mouse Models: Approaches, Relevance, and Standardization, Christopher A. Waker, Melissa R. Kaufman, and Thomas L. Brown
Calcium Homeostasis in Parvalbumin Drg Neurons Is Altered After Sciatic Nerve Crush and Sciatic Nerve Transection Injuries, Marie C. Walters and David R. Ladle
The Role of Action Potential Waveform in Failure of Excitation Contraction Coupling, Xueyong Wang, Murad Nawaz, Steve R.A. Burke, Roger Bannister, Brent D. Foy, Andrew A. Voss, and Mark M. Rich
Submissions from 2020
Effects of Neuronic Shutter Observed in the EEG Alpha Rhythm, Kevin E. Alexander, Justin R. Estepp, and Sherif M. Elbasiouny
Phagocytic Activity of Splenic Macrophages Is Enhanced and Accompanied by Cytosolic Alkalinization in TRPM7 Kinase-Dead Mice, Pavani Beesetty, Jananie Rockwood, Taku Kaitsuka, Tetyana Zhelay, Siham Hourani, Masayuki Matsushita, and J. Ashot Kozak
Neuromuscular Junction Transmission Failure Is a Late Phenotype in Aging Mice, Deepti Chugh, Chitra C. Iyer, Xueyong Wang, Prameela Bobbili, Mark M. Rich, and W. David Arnold
TRPV4 Antagonism Prevents Mechanically Induced Myotonia, Chris Dupont, Kevin Novak, Kristen Denman, Jessica H. Myers, Jeremy M. Sullivan, Phillip V. Walker II, Nicklaus L. Brown, David R. Ladle, Laurent Bogdanik, Cathleen M. Lutz, Andrew A. Voss, Charlotte J. Sumner, and Mark M. Rich
Divergent Synaptic Scaling of Miniature EPSCs following Activity Blockade in Dissociated Neuronal Cultures, Amanda L. Hanes, Andrew G. Koesters, Ming-fai Fong, Haider F. Altimimi, David Stellwagen, Peter Wenner, and Kathrin L. Engisch
Meta-analysis of biological variables’ impact on spinal motoneuron electrophysiology data, Morgan M. Highlander, John M. Allen, and Sherif M. Elbasiouny
Chronic Defects in Intraspinal Mechanisms of Spike Encoding by Spinal Motoneurons Following Chemotherapy, Stephen N. Housley, Paul Nardelli, Randal K. Powers, Mark M. Rich, and Timothy C. Cope
TRPM7 Channel Activity in Jurkat T Lymphocytes During Magnesium Depletion and Loading: Implications for Divalent Metal Entry and Cytotoxicity, Alayna Mellott, Jananie Rockwood, Tetyana Zhelay, Charles Tuan Luu, Taku Kaitsuka, and J. Ashot Kozak
Central Role of Subthreshold Currents in Myotonia, Sabrina Metzger, Chris Dupont, Andrew A. Voss, and Mark M. Rich
Central Role of Subthreshold Currents in Myotonia, Sabrina Metzger, Chris Dupont, Andrew A. Voss, and Mark M. Rich
Dendritic Distributions of L-type Ca2+ and SKL Channels in Spinal Motoneurons: A Simulation Study, Mohamed H. Mousa and Sherif M. Elbasiouny
Multi-Walled Carbon Nanotube Carpets as Scaffolds for u87mg Glioblastoma Multiforme Cell Growth, Soham D. Parikh, Soham Dave, Luping Huang, Wenhu Wang, Sharmila M. Mukhopadhyay, and Debra A. Mayes
Effects of TRPM7 Kinase Inactivation in Macrophages, Jananie Rockwood, Pavani Beesetty, Masayuki Matsushita, and J. Ashot Kozak
Depressed Neuromuscular Transmission Causes Weakness in Mice Lacking BK Potassium Channels, Xueyong Wang, Steven R.A. Burke, Robert J. Talmadge, Andrew A. Voss, and Mark M. Rich
Depressed Neuromuscular Transmission Causes Weakness in Mice Lacking BK Potassium Channels, Xueyong Wang, Steven R.A. Burke, Robert J. Talmadge, Andrew A. Voss, and Mark M. Rich
COVID 19 What You Need to Know, Dawn P. Wooley, Giancarlo Mariani, Craig Woolley, and Laura M. Luehrmann
Submissions from 2019
Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation, Erica Tracey Akhter, Ronald W. Griffith, Arthur W. English, and Francisco J. Alvarez
Sciatic Nerve Cut and Repair Using Fibrin Glue in Adult Mice, Erica T. Akhter, Travis M. Rotterman, Arthur W. English, and Francisco J. Alvarez
Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction, Renee E. Albers, Melissa R. Kaufman, Bryony V. Natale, Chanel Keoni, Kashmira Kulkarni-Datar, Sarah Min, Clintoria R. Williams, David R.C. Natale, and Thomas L. Brown
A Motor Physiology Recurrent Topic: Simplify Assumptions to Gain Extra Insight, Francisco J. Alvarez
Treatment of Myotonia Congenita With Retigabine in Mice, Chris Dupont, Kirsten S. Denman, Ahmed A. Hawash, Andrew A. Voss, and Mark M. Rich
Automated Cell-Type Classification and Death-Detection of Spinal Motoneurons, Mai Gamal, Mohamed H. Mousa, Seif Eldawlatly, and Sherif M. Elbasiouny
Genetic and Pharmacological Inactivation of Apical NA+-K+-2cl− Cotransporter 1 in Choroid Plexus Epithelial Cells Reveals the Physiological Function of the Cotransporter, Jeannine MC Gregoriades, Aaron Madaris, Francisco J. Alvarez, and Francisco J. Alvarez-Leefmans
Open-Label Trial of Ranolazine for the Treatment of Paramyotonia Congenita, Samantha Lorusso, David Kline, Amy Bartlett, Miriam Freimer, Julie Agriesti, Ahmed A. Hawash, Mark M. Rich, John T. Kissel, and W. David Arnold
The Mechanistic Basis for Successful Spinal Cord Stimulation to Generate Steady Motor Outputs, Amr A. Mahrous, Mohamed H. Mousa, and Sherif M. Elbasiouny
Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism, Travis M. Rotterman, Erica T. Akhter, Alicia R. Lane, Kathryn P. MacPherson, Violet V. Garcia, Malu G. Tansey, and Francisco J. Alvarez
Self-Directed Down-Regulation of Auditory Cortex Activity Mediated by Real-Time fMRI Neurofeedback Augments Attentional Processes, Resting Cerebral Perfusion, and Auditory Activation, Matthew Sherwood, Jason G. Parker, Emily E. Diller, Subhashini Ganapathy, Kevin B. Bennett, Carlos R. Esquivel, and Jeremy T. Nelson
Calcium Imaging of Parvalbumin Neurons in the Dorsal Root Ganglia, Marie C. Walters, Martha Sonner, Jessica H. Myers, and David R. Ladle
Initial Characterization of the Indole-3-Carboxamide Bic-154 as a Fast Onset and Reversible ORAI Channel Blocker, Tetyana Zhelay, Kalina Szteyn, Elisa Liardo, Jae Eun Cheong, Steffi Koerner, Anil Ekkati, Lijun Sun, and J. Ashot Kozak
Submissions from 2018
Protect NIH's DNA Advisory Committee, Zach N. Adelman, Lorraine M. Albritton, Kathleen Boris-Lawrie, Michael J. Buchmeier, Paula Cannon, Mildred Cho, David DiGiusto, J Kevin Donahue, Howard J. Federoff, Marie-Louise Hammarskjold, Angelica D. Hardison, Benhur Lee, Dean Anthony Lee, Matthew H. Porteus, Lainie Friedman Ross, Susan R. Ross, Dawn P. Wooley, and Laurie Zoloth
TGF-β induces Smad2 phosphorylation, ARE induction, and trophoblast differentiation, Renee E. Albers, Kaisa Selesniemi, David R.C. Natale, and Thomas L. Brown
Gestational differences in murine placenta: Glycolytic metabolism and pregnancy parameters, Renee E. Albers, Christopher A. Waker, Chanel Keoni, Melissa R. Kaufman, Michael A. Bottomley, Sarah Min, David R. Natale, and Thomas L. Brown
The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors, John M. Allen and Sherif M. Elbasiouny
Spinal Interneurons “à La Carte”, Francisco J. Alvarez
N-Acetylcysteine Modulation of Mitochondrial Respiration and Blood Brain Barrier Permeability Is Time Dependent and Cell Type Specific, Alim S El Amouri, Christopher A. Waker, Luping Huang, Cameron L. Smith, and Debra A. Mayes
Inactivation of TRPM7 Kinase in Mice Results in Enlarged Spleens, Reduced T-Cell Proliferation and Diminished Store-Operated Calcium Entry, Pavani Beesetty, Krystyna Blanka Wieczerzak, Jennifer Gibson, Taku Kaitsuka, Charles Tuan Luu, Masayuki Matsushita, and J. Ashot Kozak
The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis, S. Shekar Dukkipati, Teresa L. Garrett, and Sherif M. Elbasiouny
Gender- and Region-Specific Changes in Estrogen Signaling in Aging Rat Brain Mitochondria, Christopher M. Evola, Tanner L. Hudson, Luping Huang, Adrian M. Corbett, and Debra A. Mayes
Preventing Acute Asthmatic Symptoms by Targeting a Neuronal Mechanism Involving Carotid Body Lysophosphatidic Acid Receptors, Nicholas G. Jendzjowsky, Arijit Roy, Nicole O. Barioni, Margaret M. Kelly, Francis HY Green, Christopher N. Wyatt, Richard L. Pye, Luana Tenorio Lopes, and Richard A. Wilson
Modulation of SK channels regulates locomotor alternating bursting activity in the functionally-mature spinal cord, Amr A. Mahrou and Sherif M. Elbasiouny
Activation of TRPV4 Stimulates Transepithelial Ion Flux in a Porcine Choroid Plexus Cell Line, Daniel Preston, Stefanie Simpson, Dan R. Halm, Alexandra Hochestetler, Christian Schwerk, Horst Schroten, and Bonnie L. Blazer-Yost
High Fat Feeding in Rats Alters Respiratory Parameters by a Mechanism That Is Unlikely to Be Mediated by Carotid Body Type I Cells, Ryan J. Rakoczy, Richard L. Pye, Tariq Hasan Fayyad, Joseph Michael Santin, Barbara L. Barr, and Christopher N. Wyatt
Acute Oxygen Sensing by the Carotid Body: A Rattlebag of Molecular Mechanisms, Ryan J. Rakoczy and Christopher N. Wyatt
Repetitive Transcranial Electrical Stimulation Induces Quantified Changes in Resting Cerebral Perfusion Measured From Arterial Spin Labeling, Matthew Sherwood, Aaron T. Madaris, Casserly R. Mullenger, and R. Andy McKinley
Single Session Low Frequency Left Dorsolateral Prefrontal Transcranial Magnetic Stimulation Changes Neurometabolite Relationships in Healthy Humans, Matthew Sherwood, Richard A. McKinley, Danielle Boeke, Jason G. Parrker, Lindsey K. McIntire, Justin M. Nelson, Catherine Fletchall, Natasha Alexander, Amanda McConnell, Chuck Goodyear, Jeremy T. Nelson, and Nathaniel R. Bridges
Volitional Down-Regulation of the Primary Auditory Cortex Via Directed Attention Mediated by Real-Time fMRI Neurofeedback, Matthew Sherwood, Jason G. Parker, Emily E. Diller, Subhashini Ganapathy, Kevin B. Bennett, and Jeremy T. Nelson
Facilitation of Antagonist Motor Output Through Short-Latency Sensory Pathways During Postnatal Development in the Mouse, Patrick M. Sonner and David R. Ladle
Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction, Xueyong Wang, J. Michael McIntosh, and Mark M. Rich
Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction, Xueyong Wang, J. Michael McIntosh, and Mark M. Rich
Homeostatic Synaptic Plasticity at the Neuromuscular Junction in Myasthenia Gravis, Xueyong Wang and Mark M. Rich
TRPM7 Current Inactivation: Evidence for Inside-Out Signaling, Tetyana Zhelay and J. Ashot Kozak
Depletion of Plasma Membrane–Associated Phosphoinositides Mimics Inhibition of TRPM7 Channels by Cytosolic Mg2+, Spermine, and pH, Tetyana Zhelay, Krystyna Blanka Wieczerzak, Pavani Beesetty, Gerald M. Alter, Masayuki Matsushita, and J. Ashot Kozak
Submissions from 2017
Gephyrin and the Regulation of Synaptic Strength and Dynamics at Glycinergic Inhibitory Synapses, Francisco J. Alvarez
Open-Label Trial of Ranolazine for the Treatment of Myotonia Congenita, W. David Arnold, David Kline, Alan Sanderson, Ahmed A. Hawash, Amy Bartlett, Kevin R. Novak, Mark M. Rich, and John T. Kissel
Ventilatory and Chemoreceptor Responses to Hypercapnia in Neonatal Rats Chronically Exposed to Moderate Hyperoxia, Ryan W. Bavis, Ke-yong Li, Kathryn J. DeAngelis, Ryan J. March, Josefine A. Wallace, Sarah Logan, and Robert W. Putnam
Regulation of TRPM7 by Cytosolic Mg2+ and pH: Insights from VSP Expression, Pavani Beesetty, Krystyna Blanka Wieczerzak, Tatyana Zhelay, Taku Kaitsuka, Masayuki Matsushita, and J. Ashot Kozak
Experimental design and data analysis issues contribute to inconsistent results of C-bouton changes in amyotrophic lateral sclerosis, S. Shekar Dukkipati, Aouatef Chihi, Yiwen Wang, and Sherif M. Elbasiouny
Cross-Disciplinary Medical Advances with Neuroengineering: Challenges Spur Development of Unique Rehabilitative and Therapeutic Interventions, Sherif Elbasiouny
Characterization of Calbindin D28k Expressing Interneurons in the Ventral Horn of the Mouse Spinal Cord, Taylor L. Floyd, Yiyun Dai, and David R. Ladle
Survival and Growth of C57BL/6J Mice Lacking the BK Channel, Kcnma1: Lower Adult Body Weight Occurs Together with Higher Body Fat, Susan T. Halm, Michael A. Bottomley, Mohammed M. Almutairi, Mauricio Di Fulvio, and Dan R. Halm
Inhibiting Persistent Inward Sodium Currents Prevents Myotonia, Ahmed A. Hawash, Andrew A. Voss, and Mark M. Rich
Depressed Synaptic Transmission and Reduced Vesicle Release Sites in Huntington's Disease Neuromuscular Junctions, Ahmad Khedraki, Eric J. Reed, Shannon H. Romer, Qingbo Wang, William Romine, Mark M. Rich, Robert J. Talmadge, and Andrew A. Voss
The Neuronal K+CL− Co-Transporter 2 (Slc12a5) Modulates Insulin Secretion, Shams Kursan, Timothy S. McMillen, Pavani Beesetty, Eduardo Dias-Junior, Mohammed M. Almutairi, Abu A. Sajib, J. Ashot Kozak, Lydia Aguilar-Bryan, and Mauicio Di Fulvio
SK channel inhibition mediates the initiation and amplitude modulation of synchronized burst firing in the spinal cord, Amr A. Mahrous and Sherif M. Elbasiouny
Simulation of dendritic L-type ca channels' warm-up phenomenon in spinal motoneurons, Mohamed H. Mousa, Ahmed H. Kandil, and Sherif M. Elbasiouny
Increasing Motor Neuron Excitability to Treat Weakness in Sepsis, Paul Nardelli, Randall Powers, Tim C. Cope, and Mark M. Rich
Dicer Maintains the Identity and Function of Proprioceptive Sensory Neurons, Sean M. O'Toole, Monica M. Ferrer, Jennifer Mekonnen, Haihan Zhang, Yasuyuki Shima, David R. Ladle, and Sacha B. Nelson
Refining Forelimb Asymmetry Analysis: Correlation with Montoya Staircase Contralateral Function Post-stroke, Moner A. Ragas, Devipriyanka Nagarajan, and Adrian M. Corbett
Distinct Roles for Motor Neuron Autophagy Early and Late in the sod1g93a Mouse Model of Als, Noam D. Rudnick, Christopher J. Griffey, Paolo Guarnieri, Valeria Gerbino, Xueyong Wang, Jason A. Piersaint, Juan Carlos Tapia, Mark M. Rich, and Tom Maniatis
VGLUT1 Synapses and P-Boutons on Regenerating Motoneurons After Nerve Crush, Adam J. Schultz, Travis M. Rotterman, Anirudh Dwarakanath, and Francisco J. Alvarez
A Protocol for the Administration of Real-Time fMRI Neurofeedback Training, Matthew Sherwood, Emily E. Diller, Elizabeth Ey, Subhashini Ganapathy, Jeremy T. Nelson, and Jason G. Parker
