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Theses/Dissertations from 2023

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Regulation of ERK3 by KRAS Signalling and its Role in the Growth of Lung Adenocarcinoma (LUAD) Cells, Shreya Akunapuram

Theses/Dissertations from 2022

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The Role of PI4KB in Cellular Localization of Small GTPases, Parisa Sadrpour

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Instability and Extrachromosomal Circular DNA Formation at Microsatellites and Unstable DNA Sequences, Matilyn M. Shanahan

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Reconstruction of Gut Microbiome via Intermittent Feeding, Kourtney Sprague

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Genomic instability at a polypurine/polypyrimidine repeat sequence, Nathen S. Zavada

Theses/Dissertations from 2021

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Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat, Andrew Blake Austin Browder

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Enzymatic Post-Translational Halogenation for Adding Functionality to Biomaterials, Alexander L. Compean

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Microsatellites and Their Association with Break Induced Replication, French J. Damewood IV

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Microsatellites and Their Association with Break Induced Replication, French J. Damewood IV

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Potential Drug Treatment for Duchenne Muscular Dystrophy Which Could be Through Upregulation of Lipin1, Rajsi Y. Thaker

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The F-box Protein FBW7 Negatively Regulates the Stability of ERK3 Protein, Nicole Walters

Theses/Dissertations from 2020

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Alternative Splicing of MDM4 in Human Melanomas, Abdullah Salem S. Alatawi

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Apoptosis and Necrosis Drive Muscle Fiber Loss in Lipin1 Deficient Skeletal Muscle, Sandhya Ramani Sattiraju

Theses/Dissertations from 2019

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∆Np63α Positively Regulates ERK3 Expression in Non-Melanoma Skin Cancer, Eid Salem Alshammari

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ERK3 negatively regulates the IL-6/STAT3 signaling via SOCS3, Astha Shakya

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Genotyping for Response to Physical Training, Stacy Simmons

Theses/Dissertations from 2018

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Avicin is a potent sphingomyelinase inhibitor that blocks K-Ras plasma membrane interaction and its oncogenic activity, Christian M. Garrido

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A Novel Method to Analyze DNA Breaks and Repair in Human Cells, Caitlin Elizabeth Goodman

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Lipin1 regulates skeletal muscle differentiation through the PKC/HDAC5/MEF2c:MyoD -mediated pathway, Abdulrahman M. Jama

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Discovery of small molecules blocking oncogenic K-Ras activity, Sarah E. Kovar

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Availability of Fermentable Nutrients Affect Gut Microbiota Composition, Trupthi Mehta

Theses/Dissertations from 2017

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Role of ERK3 in Regulating RhoGDI1-PAKs Signaling Axis, Hitham Abdulrahman Aldharee

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DNp63a Suppresses Cell Invasion by Targeting rac1 Through miR-320a, Amjad Ahmed Aljagthmi

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Exploring the Role of lipin1 in Mitophagy Process Using lipin1 Deficient-EGFP Tagged lC3 Transgenic Mice, Abdullah Ali Alshudukhi

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ERK3 as a BRAF-Regulated Tumor Suppressor is a New Potential Cancer Target in Melanoma, Minyi Chen

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Urinary Metabolomics to Detect Polycystic Kidney Disease at Early Stage, Amnah Mahmoud Obidan

Theses/Dissertations from 2016

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Functional characterization of cancer-related mutations of ERK3, Hadel Mohammed Alsaran

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Effects of Synthetic Ligands on Heterodimer Pairs Regarding Full-Length Human PPARα, RXRα and LXRα, Emily Delman

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Instability at Trinucleotide Repeat DNAs, Rujuta Yashodhan Gadgil

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Biomimetic Production Techniques for Mechanical and Chemical Characterization of Sucker Ring Teeth Isoform-12 From the Dosidicus Gigas Squid, Marcus T. Grant

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Novel Insight into the Role of LXRα in Metabolic Regulation via DNA Binding as a Heterodimer with PPARα and as a Homodimer, Andrea M. Klingler

Theses/Dissertations from 2015

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Purification of Recombinant Δ Np63 α and Characterization of Peptide Binding, Amal Abdulah Albati

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Analysis of Chromatin Accessiblity of the Human c-myc Replication Origin, Tu Thien Danh

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Identifying the Amino Acids Important for HIV Rev-Tubulin Interactions, Bruce E. Dukes II

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Distinguishing Melanocytic Nevi from Melanoma by DNA Copy Number Changes: Array-Comparative Genomic Hybridization as a Research Tool, Ahmed Ibrahim Mahas

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Differences in Fecal Metabolite Profiles from Geographically Distinct Populations of Adolescents, Jessica Moncivaiz

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Improving DNA Quality using FFPE tissues for Array Comparative Genomic Hybridization to find Single Nucleotide Polymorphisms (SNPs) in Melanoma, Keerti Potluri

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Profiling Fatty Acid Composition of Brown Adipose Tissue, White Adipose Tissue and Bone Marrow Adipose Tissue of Healthy and Diet-Induced Obese Mice, Urszula Osinska Warncke

Theses/Dissertations from 2014

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Investigating the Undefined Role of Subunit IIIin Cytochrome c Oxidase Functioning Using Dicyclohexylcarbodiimide Chemical Modification; Insight Into Enzyme Structure and Molecular Mechanism, Kelli Nicole Fisher

Theses/Dissertations from 2013

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Histone Deacetylation as a Mechanism of YPEL3 Down-Regulation in ER-a Positive Breast Cancer Cell Lines, Remah Ali

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Fabrication of Responsive Polymer Brushes for Patterned Cell Growth and Detachment, Ashley B. Sutherland

Theses/Dissertations from 2012

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Study of MicroRNA-34a mediated post transcriptional regulation of MDM4, Pooja P. Mandke

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Exploration of YPEL3 Response to Hormones and Ability to Induce Senescence, Joseph E. Rotsinger

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Lipase-Kinase Associations Involving PLD2, JAK3 and FES that Underlie Cancer Cell Proliferation and Invasion, Qing Ye

Theses/Dissertations from 2011

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Structural and Functional Alteration of Full Length PPARα and LXRα by Fatty Acids and their Thioesters, Madhumitha Balanarasimha

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Interrogation of the Distal Gut Microbiota of Healthy Adolescents and those with Irritable Bowel Syndrome, Laura J. Rigsbee

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Functional Metabolomics' Enhances Assessment of Tissue Dysfunction as Demonstrated in a Rat Model of Sub-Acute D-Serine Exposure, Isaie Sibomana

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Bio-Functionalized Clay Nanoparticles for Wound Healing Applications, Christopher Anthony Vaiana

Theses/Dissertations from 2010

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Inhibition of Cell Invasion by Targeting PLD, Terry C. Farkaly

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Characterization of Three Mutations in Conserved Domain of Subunit III of Cytochrome c Oxidase from Rhodobacter sphaeroides, Rachel Omolewu

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Genetic Studies of Genes Involved in the Initiation of DNA Replication in the Fission Yeast Schizosaccharomyces Pombe, Zhuo Wang

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P63 and VDR are regulated by Vitamin D (VD3) and UV signaling, Andrew J. Whitlatch

Theses/Dissertations from 2009

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Dose-Dependent Effects of Oxygen on Metabolism in Rat Cortico-Hippocampal Brain Tissue Slices, Jennifer Lynne Hollyfield

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DUE-B, A New Human DNA Replication Protein, is the Functional Homolog of S. Cerevisiae SLD3, Jianhong Yao

Theses/Dissertations from 2008

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Transcriptional regulation of LAMB3 by p53, Meghna Jani

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Validation Of A Custom-made Microarray To Study Human Intestinal Microflora, Harshavardhan Kenche

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Mdm2 Amplification in Nih3t3l1 Preadipocytes Leads to Mdm2 Elevation in Terminal Adipogenesis, Vaughn Litteral

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NMR Analyses Show TCDD Elicits Differences in Hepatic Metabolism in Female C57BL/6 Mice and Sprague-Dawley Rats, Meghan Katherine Makley

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In Search For New p53 Regulated Genes, Meldrick Daniel Mpagi

Theses/Dissertations from 2007

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DUE-B in Chromatin and Nuclear Speckles, Nadia Katrangi

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Differential effects of mutant TAp63γ on transactivation of p53 and/or p63 responsive genes and their effects on global gene expression, Shama Khan Khokhar

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Detection and Destruction of Escherichia Coli Bacteria and Bacteriophage Using Biofunctionalized Nanoshells, Joseph E. Van Buren

Theses/Dissertations from 2005

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Characterization of Photosynthetic Reaction Centers from Bradyrhizobium Strain BTAi 1, Isaac P. Forquer