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Theses/Dissertations from 2023

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To Determine the Role of the Platelet Activating Factor - Receptor in FOLFIRINOX Therapy-mediated Microvesicles Particle Generation, Krishna Awasthi

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Regulation of Cathepsin L Expression and Activity by Cell Confluence and the Circadian Clock, Prashant Gaikwad

Theses/Dissertations from 2022

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Impaired β-Cell Neogenesis in a Mouse Model of Metabolic Syndrome, Modhi Abdullah Alshammari

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Replication Stress Induced by the Ribonucleotide Reductase Inhibitors Guanazole, Triapine, and Gemcitabine in Fission Yeast, Mashael Yahya A Alyahya

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Heightened Levels of Microvesicle Particles Resulting from Combination of Ethanol and Thermal Burn Injury, Chad Alan Brewer

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AhR-mediated Transcriptional Regulation of the Human Immunoglobulin Hs1.2 Enhancer, Sydney White

Theses/Dissertations from 2021

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The Effect of Circadian Clock Modulation on Cisplatin Cytotoxicity, Nadeen Nibal Ahmad Anabtawi

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Stress-Induced Senescence in Human Dermal Fibroblasts : Effects of Creatine and Nicotinamide Post Stress Treatment, Venkata Sravya Arikatla

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Functions of ATR Kinase in Terminally Differentiated Human Epidermal Keratinocyles and in Human Ex-Vivo Skin After Exposure to Ultraviolet B Radiation, Vivek Shashank Nag Gogusetti

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Xeroderma Pigmentosum A Deficiency Results in Increased Generation of Microvesicle Particles in Response to Ultraviolet B Radiation, Christian Lea Rajeshkumar

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The Protective Effects of miR-210 Modified Endothelial Progenitor Cells Released Exosomes in Hypoxia/Reoxygenation Injured Neurons, Sri Meghana Yerrapragada

Theses/Dissertations from 2020

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Insulin-like growth factor-1 (IGF-1) impacts p53-regulated gene products in UVB-irradiated human keratinocytes and skin epidermis, Abdulrhaman Mohammed Mohammed Alkawwar

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Multiple Genotoxic Agents Activate ATR Kinase Signaling in Quiescent Human Cells, Mariyyah Ahmed O. Madkhali

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Effects of Creatine and Nicotinamide on Experimentally Induced Senescence in Dermal Fibroblasts, Avinash Satyanarayan Mahajan

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Identification of New Metabolic Mutations in the Fission Yeast Schizosaccharomyces pombe that Sensitize the Cell to Hydroxyurea, Alaa Mahdi

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Topical Photodynamic Therapy Generates Microvesicle Particles, Oladayo Ayobami Oyebanji

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Role of exercise in macrophage polarization of perivascular adipose tissue and adipose tissue inflammation in hypertensive mice model, Venkata Sai Usha Sri Polaki

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Low dose UV-B induced keratinocyte exosomes protect Schwann cells against high glucose injury, Kartheek Pothana

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The Feeding Pattern of C57BL/6J Mice, Yakshkumar Dilipbhai Rathod

Theses/Dissertations from 2019

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Effect of Endothelial Progenitor Cell-derived Exosomes on High Glucose and Hypoxia/ Reoxygenation-induced Injury of Astrocytes, Manasi Suchit Halurkar

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Identification of New Metabolic Mutations that Enhance the Cell-Killing Effect of Hydroxyurea, A Clinically Used Drug with Multiple Implications, Rittu Elsa Samuel

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Differing functions of ATR kinase in human epidermal keratinocytes exposed to Ultraviolet B Radiation, Kavya Shaj

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Kinetics of Microvesicle Particle Release in Keratinocytes, Pariksha Thapa

Theses/Dissertations from 2018

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Regulation of Microvesicle Particle Release in Keratinocytes, Azeezat Afolake Awoyemi

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Nanomaterial Charge-Dependent Platelet Activating Factor Receptor Agonism in Human Epidermal Cells, Shahryar Jamshed Qureshi

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Exosomes Released from Multiple Myeloma Cells Influence the Angiogenic Function of Endothelial Cells by Regulating MicroRNA-29b, Qinmao Ye

Theses/Dissertations from 2017

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Usage of Extracellular Microvesicles as Novel and Promising Therapeutic Tool in Wound Healing, Sami Gamaleddin F. Alsabri

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Effect of Hyperglycemia and Thiazolidinediones on Cardiac Angiotensin Converting Enzyme 2 (ACE2) and Neprilysin (NEP) in db/db Diabetic Mice, Rucha Fadnavis

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Effect of hyperglycemia and thiazolidinediones on cardiac angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db diabetic mice., Rucha Fadnavis

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Thermal Burn Injury Induced Microvesicle Particle Release, Katherine Erin Fahy

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Extracellular Microvesicles as a Novel Biomarker for Wound Healing, Walid Omran Mari

Theses/Dissertations from 2016

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Effect of Oasis-Ultra Matrix on the Healing Rate of Stage IV Pressure Wounds, Abdelfatah Shaban Abou Issa

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Examining Infarct Sizes in Female Sprague Dawley Rats in Response to a Delayed Post-Stroke Pharmacological Treatment in Combination with Physical Rehabilitation, Sayali Ravindra Dharmadhikari

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Interaction of Na+/K+ ATPase with Bcl-2 Proteins: Isolated Enzyme vs Epithelial Cell Extracts, Chandra Kumar Maharjan

Theses/Dissertations from 2015

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Role of Angiotensin II Type 1A Receptors on Renal and Urinary Angiotensin Converting Enzyme 2 (ACE2) and Neprilysin (NEP) in the Two-Kidney One-Clip (2K1C) Model of Renovascular Hypertension, Laale F. Alawi

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Interaction between Na/ K-ATPase and BCL-2 Proteins BCLXL and BAK, Tariq M. Alqahtani

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Na+/K+ Pump and Cl--coupled Na+ and K+ co-transporters in Mouse Embryonic Fibroblasts lacking the Tuberous Sclerosis Complex TSC1 and TSC2 genes., Jasser Ali S. Alzhrani

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The Role of NKCC2A on the Nervous System Activity, Kavya Annu

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Differential Effects of The AhR on Immunoglobulin Gene Expression in Human B Cells, Naga Lakshmi Kaulini Burra

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Behavior of Gold Nanoparticles in Physiological Environment and the Role of Agglomeration and Fractal Dimension, Rose Cooper

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Developing Proteomic and Cytokine Biomarkers for Vulvodynia, Ashvin Iyer

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Identification and Quantification of the Collagen Type I, III and V in Rabbit Patellar Tendons, Mahesh Chandra Kodali

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Endothelial Cell Derived MVs and Exosomes: Release and Functional Study, Langni Liu

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Expression of Aquaporins in Mouse Choroid Plexus and Ependymal Cells, Pankaj Patyal

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Effect of progesterone, terbutaline and leptin on the function of alveolar type II cells, Shamili Sammohi

Theses/Dissertations from 2014

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Inactivation of At1A Receptors Attenuate Lactate Accumulation and Improve Cardiac Performance and Acid-Base Homeostasis during Endurance Exercise, Ahmad Mohammed Alhajoj

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Role of Bumetanide on Insulin Secretion, Mohammed Mashari Almutairi

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The Modulatory Role of Circulating Microvesicles in Endothelial Progenitor Cell Function is Altered in T2DM, Hala Mustafa Ammar

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Early Increase of CD11c in Human Monocyte-Derived Dendritic Cells in the Presence of A/California/07/2009 (H1N1pdm), Amber M. Braddock

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Increased Urinary Angiotensin Converting Enzyme 2 (ACE2) and Neprilysin (NEP) in Type 2 Diabetic Patients, Sridevi Gutta

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Expression, Characterization, Cloning and Functional Impact of Slc12a5 in the Endocrine Pancreas, Shams Kursan

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Characterization of Small Conductance Calcium-Activated Potassium Channels in a Human Lens Epithelium Cell Line (B3), Wedad Ali Saqar

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Effect of the Broad-Spectrum Caspase Inhibitor Q-VD-OPh on Neurodegeneration and Neuroinflammation of Sarin Exposed Mice, Ekta J. Shah

Theses/Dissertations from 2013

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Chronic Swim Stress Attenuates Endocrine Response and Improves Cardiac Function in Mice Lacking the Angiotensin II Type 1a Receptor, Najat Khalifa Almahroug

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Role of bax, ibpA, ibpB and cspH Genes in Protecting CFT073 (Uropathogenic Escherichia coli) Against Salt and Urea Stress, Pavani Beesetty

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"Characterization of Red Diamondback Rattlesnake Venom Proteins on Cell Death and Function", Venus Ebrahimian

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Bioaccumulation and Neuroinflammation of Gold Nanoparticles in the Central Nervous System, Fahimeh Fallahi

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Effects of Red Diamondback Rattlesnake Venom on Keloid Dermal Fibroblasts In Vitro, Mackenzie Shelby Newman

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K-Cl Cotransport: Role of KCC3 in cellular Potassium (K) homeostasis in KCC3- Transfected HEK-293 cells, Nagendra Babu Ravilla

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Insulin Treatment Attenuates Renal ADAM17 and ACE2 Shedding in Akita Diabetic Mice, Esam Said Busah Salem

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Physical Exercise Training but Not Metformin Attenuates Albuminuria and Shedding of ACE2 in Type 2 Diabetic db/db Mice, Hari Krishna Somineni

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Locating Chelerythrine, an Alkaloid, within a Cytosolic Environment by Maldi-Tof Mass Spectrometry, Bradley Allen Williams

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The Aryl Hydrocarbon Receptor Regulates an Essential Transcriptional Element in the Immunoglobulin Heavy Chain Gene, Michael J. Wourms

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Effects of Ang 1-7 and Endothelial Microvesicles on Ang II-induced Dysfunction and Apoptosis in Cerebral Endothelial Cells, Xiang Xiao

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Tolfenamic Acid Induces Cell Apoptosis and Inhibits Collagen Accumulation in Keloid Fibroblasts, Dan Yi

Theses/Dissertations from 2012

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Enhanced Angiotensin II-Induced Cardiac and Aortic Remodeling in ACE2 Knockout Mice, Mahmoud Alghamri

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Role of Na+K+2Cl- Co-transporters in Insulin Secretion, Saeed Alshahrani

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Use of Phage Display Libraries to Select For B-cell Receptor-specific Peptides of Chronic Lymphocytic Leukemia Cells, Richard M. Chou

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Evaluation of CM-2,525 as a Neuroprotectant Against Sarin: A Comparison with 8-OH-DPAT, Amanda R. Furman

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Elucidating Transcription Factor Regulation by TCDD within the HS1,2 Enhancer, Sharon D. Ochs

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Light-Limited Access to Fructose Alters Metabolic Function and Adipose Tissue Catecholaminergic Activity in Mice, Naima Salem Rodwan

Theses/Dissertations from 2011

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Response of Neuroinflammatory and Neurodegenerative Markers Following Sub-lethal Sarin Exposure and Subsequent Treatment via an in-vivo Caspase Inhibitor, Douglas F. Chmura

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Role Of Hyperglycemia and Aldosterone on Renal ACE2 aND Albuminuria in db/db Mice, Harshita Chodavarapu

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Analysis of Archived Dried Blood Spots by Mass Spectrometry for Vitamin D and Real-time PCR for Its Enzymes and Receptor, Amod N. Joshi

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Response of Monovalent Cation Transporters to Pro-apoptotic Protein Kinase C Modulators in Human Lens Epithelial Cells, Michael Anthony Lepera

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Synthesis, Characterization and Manipulation of Creighton Silver Nanoparticles for Future Cytotoxicity Studies, Sesha Lakshmi Paluri

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Low Dose Nerve Agent Sarin Causes Dilated Cardiomyopathy and Autonomic Imbalance in Mice, Swapnil Vijay Shewale

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Differentiation of Megakaryocytes/Platelets and Neurons from Human Endometrial Stromal Progenitor Cells, Jinju Wang

Theses/Dissertations from 2010

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2,3,7,8-Tetrachlordibenzo-p-dioxin Mediated Immune Suppression through Interactions at the 3'Immunoglobulin Heavy Chain Regulatory Region Enhancers, David Harold Ellis

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Hyperbaric Oxygen in the Prevention of Carbon Monoxide Induced Delayed Neurological Sequelae in Male Sprague Dawley Rats (Rattus norvegicus), Chester P. Gut Jr.

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Tissue Specific Effects of Adipose Stem Cells (ASC) in a Melanoma Tumor Environment, Drew Michael Nedderman

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Quantitative Structure-Activity Relationships for Organophosphates Binding to Trypsin and Chymotrypsin, Christopher Daniel Ruark

Theses/Dissertations from 2009

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In-Vitro Biocompatibility of Silver Nanoparticles Anchored on Multi-Walled Carbon Nanotubes, Alicia Brooks Castle

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Ischemic Stroke in Type II Diabetic Mice: Deregulation of SDF-1a/CXCR4 Axis, Avik Das

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TCDD-Induced Modulation of the HS1,2 Enhancer within the 3'Immunoglobulin Heavy Chain Regulatory Region, Tharu M. Fernando

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Effects of Chlorpyrifos-oxon on Prohormone Convertase Enzyme Activity, Sean William Harshman

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Novel Neuroprotectants for Sarin plus CBDP Induced Convulsions, Kaushal V. Joshi

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Effects of Direct Mechanical Ventricular Actuation on the Apoptotic Signaling of a Failing Heart, Scott Kerns

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Impact of Diabetes on ACE/ACE2 Balance and Angiotensin II Type 1 Receptor Expression in db/db Diabetic Mice, Malav Navinchandra Madhu

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Effect of Low-Dose Sarin Exposure on the Neurochemistry of Different Brain Structures in Mice, Dhawal Pravin Oswal

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Characterization of Infectivity and Pathogenesis of Partially Reconstructed 1918 and Highly Pathogenic Avian Influenza Viruses In The BALB/C Mouse Model, John Allen Pyles

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Identification of Potential Protein Biomarkers of Low Level Kidney Degradation, Christopher Lee Woolard

Theses/Dissertations from 2007

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Neurodegeneration and Neuroinflammation in a Mouse Model of Sarin Exposure, Molly Elizabeth Davidson

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The Processing of β-Endorphin in Morphine Treated Rats Using SELDI-TOF Mass Spectrometry, Jennifer Y. Edwards

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Role of Angiotensin Converting Enzymes Ace and Ace2 in Diabetes Induced Cardiovascular Dysfunction, Keerthy Kanakamedala

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Angiotensin AT1 Receptor Blockade Protects the Brain from Ischemic Damage, Madhuri Penchikala

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Oral LD50 of Botulinum Toxin Serotype A in Guinea Pigs, Christina Marie Wilhelm

Theses/Dissertations from 2006

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In Vitro Toxicity Assessment of Silver Nanoparticles in Rat Alveolar Macrophages, Cataleya Carlson

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Kinetics and Passive Protection Efficacy Induced by Purified Ava Human Immunoglobulin G in Rabbits Against a Bacillus Anthracis Aerosol Challenge, Jennifer Lee Plahovinsak

Theses/Dissertations from 2003

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The Two Isoforms of Rat Metallothionein are Coordinately Regulated in Vivo, Diane M. Todd